Differences in Risk Factors and One-year Prognosis after Complete Revascularization in Patients with Premature Myocardial Infarction and Non-premature Myocardial Infarction
Objective To analyze the differences of risk factors between premature myocardial infarction(MI)and non-premature MI,and follow-up to observe the prognosis 1-year after cardiac revascularization.Methods Enrolled patients with myocardial infarction hospitalized in Shanghai Jiao Tong University School of Medicine Affiliated Sixth People's Hospital South Campus from September 1,2018 to November 30,2020.They were divided into two group:the young MI(premature MI)group and the non-young MI group.The basic clinical data,blood test and echocardiography of the two groups were compared.The patients were followed up by telephone or in hospital.The prognosis of the two groups during hospitalization and 1 year after cardiac revascularization were compared.Results Compared with non-young MI group,the proportion of hypertension and diabetes,high density lipoprotein-cholesterol(HDL-C),creatinine(Cr),glycosylated hemoglobin(HbA1C),B-type natriuretic peptide(BNP)were lower in young MI group(all P＜0.05),but hemoglobin,platelet count,triglyceride,alanine aminotransferase,estimated glomerular filtration rate(eGFR)and left ventricular ejection fraction(LVEF)in young Ml group were higher(all P＜0.05).One year follow-up showed that the incidence rate of heart failure in the young Ml group was lower than that in the non-young MI group(P＜0.05),while the incidence rate of bleeding events in the young MI group was higher(P＜0.05).There was no significant difference in other major cardiovascular and cerebrovascular events between the two groups.The prevalence of hypertension and diabetes in the young MI group was lower than that in the non-young MI group.Renal function decreased significantly in non-young MI group.The young MI group may had a better prognosis one year after revascularization,but had a higher risk of bleeding.Conclusion Hypertriglyceridemia,low level of HDL-C,more platelet count were risk factors for young MI.Abnormal blood lipids(especially triglycerides and high-density lipoprotein)and elevated platelet count are independent risk factors for premature MI.Premature MI has a better short-term prognosis than non-premature patients after revascularization.
Myocardial infarction in young adultsMyocardial infarctionCardiac revascularizationPrognosis
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