Relationship between Pulmonary Artery Pressure and Lung Injury Degree in Patients with Acute Respiratory Distress Syndrome
Objective To analyze the relationship between the degree of lung injury and pulmonary artery pressure in patients with acute respiratory distress syndrome(ARDS).Methods Ninety patients with ARDS who received treatment in Suzhou Hospital Benq Hospital Nanjing Medical University from August 2021 to August 2023 were selected as the observation group,and another 90 healthy patients in our physical examination center during the same period were selected as the comparison group.The degree of lung injury was assessed by LPS,and pulmonary artery pressure(PASP)was detected by color Doppler ultrasound.Acute physiology and Chronic health status Score Ⅱ(APACHE Ⅱ),lung injury degree score and PASP were compared between the two groups.ARDS patients were divided into 3 groups according to oxygenation index(OI).APACHE Ⅱ score,lung injury degree score and PASP were compared between mild,moderate and severe ARDS groups.APACHE Ⅱ score and lung injury degree score were compared between groups with and without pulmonary hypertension.Patients with pulmonary hypertension were divided into 3 groups according to pulmonary systolic blood pressure(sPAP).APACHE Ⅱ score and lung injury degree score were compared between mild pulmonary hypertension group,moderate pulmonary hypertension group and severe pulmonary hypertension group.Pearson analyzed the correlation between APACHEⅡ score,lung injury degree score and PASP.Results APACHE Ⅱ score,lung injury degree score and PASP in observation group were higher than those in comparison group(all P＜0.001).APACHE Ⅱ score,lung injury degree score and PASP in severe ARDS group were higher than those in moderate and mild groups(all P＜0.05).APACHE Ⅱ score and lung injury degree score in pulmonary hypertension group were higher than those in non-pulmonary hypertension group(all P＜0.001).APACHE Ⅱ score and lung injury degree score in severe pulmonary hypertension group were higher than those in moderate and mild groups(all P＜0.05).APACHE Ⅱ score,lung injury degree score and PASP were positively correlated(r=0.395,0.401,both P＜0.05).Conclusion The degree of lung injury in ARDS patients is positively correlated with PASP.APACHE Ⅱ score,lung injury degree score and PASP have important reference value for the assessment of patients'disease.
Acute respiratory distress syndromeAcute physiology and chronic health conditionsDegree of lung injuryPulmonary artery pressure
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