High Triglyceride-glucose Index is Associated with Severe Coronary Artery Disease and Poor Prognosis in Patients with Acute Myocardial Infarction
Objective To explore the relationship between triglyceride-glucose(TyG)index and severity of coronary artery disease and in-hospital major adverse cardiovascular events(MACEs)in patients with acute myocardial infarction(AMI).Methods A total of 360 AMI patients underwent Coronary Angiography(CAG)examination with complete clinical data from January 2022 to December 2022 in Beijing Tongren Hospital were selected for retrospectively analyzed.According to the results of CAG,Gensini score was calculated.Patients were divided to high Gensini score group(≥64 points,n=185)and low Gensini score group(＜64 points,n=175).In-hospital MACEs were recorded.Logistic regression analysis was used for risk factors analysis.Results TyG index in the high Gensini score group was higher than that in the low Gensini score group(9.18±0.06 vs 8.84±0.05,P＜0.001).Compared with the low TyG index group(＜8.98,n=180),the incidence of in-hospital MACEs was significantly higher in the high TyG index group(≥8.89,n=180)(17.2％vs 10.0％,P=0.046).Multivariate Logistic regression analysis showed that TyG index was a risk factor for high Gensini score(OR=1.59,95％CI:1.04-2.43,P=0.032)and in-hospital MACEs(OR=1.79,95％CI:1.01-3.18,P=0.045).Conclusion TyG index was associated with the severity of coronary artery disease and in-hospital MACEs in AMI patients.TyG index may predict the clinical outcomes of AMI patients.
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