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炎症性肠病与心房颤动关系的研究进展

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心房颤动(简称"房颤")是临床上最常见的心律失常,炎症反应在房颤的发生和发展中起着重要作用.炎症性肠病(IBD)是一种慢性非特异性炎症性疾病,包括克罗恩病和溃疡性结肠炎.近年来研究发现,IBD与动脉粥样硬化性心血管疾病的风险增加有关,但其与房颤的关系尚未完全明确.最近的流行病学证据表明IBD和房颤之间存在关联,特别是在发作或住院期间.本文就IBD和房颤关系、共同的致病机制以及IBD药物对房颤的影响进行综述.
Research Progress of the Relationship between Inflammatory Bowel Disease and Atrial Fibrillation
Atrial fibrillation(AF)is the most common arrhythmia in clinical practice,and the inflammatory response plays an important role in the development and progression of AF.Inflammatory bowel disease(IBD)which includes Crohn disease(CD)and ulcerative colitis(UC),is a chronic nonspecific inflammatory disease.Recent studies have found that IBD is associated with an increased risk of atherosclerotic cardiovascular disease,but its relationship with AF has not been fully clarified.Recent epidemiological evidence suggests an association between IBD and AF,especially during flares or hospitalizations.This article reviews the relationship between IBD and AF,common pathogenic mechanisms,and the impact of IBD medications on AF.

Atrial fibrillationInflammatory bowel diseaseInflammationImmune imbalance

张琪、刘改珍

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山西医科大学第二临床医学院 山西医科大学第二医院心血管内科,太原 030001

心房颤动 炎症性肠病 炎症 免疫失衡

山西省应用基础研究计划

201901D211497

2024

中国分子心脏病学杂志
中国医学科学院,中国协和医学院

中国分子心脏病学杂志

CSTPCD
影响因子:0.426
ISSN:1671-6272
年,卷(期):2024.24(1)
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