重庆市永川区水痘疫苗不同接种剂次下突破病例流行病学分析
Epidemiological analysis of breakthrough varicella under different doses of varicella vaccine in Yongchuan District,Chongqing
王亚 1周宗良 1王宏2
作者信息
- 1. 重庆市永川区疾病预防控制中心,重庆 402160
- 2. 重庆医科大学公共卫生学院
- 折叠
摘要
目的 分析重庆市永川区水痘突破病例的流行病学特征,为探索水痘的防控策略提供参考依据.方法 采用描述性流行病学方法,收集2020-2022年永川区水痘病例,分析不同接种剂次下水痘病例流行病学特征.结果 3 797例水痘病例中突破病例666例.10~<15岁无免疫史组病例最多,5~<10岁突破病例最多,差异有统计学意义(x2=13.902,P<0.05).5~<10岁的第2剂次突破病例高于10~<15岁,差异有统计学意义(x2=9.146,P<0.05).发病与末次接种间隔时间<3年的第2剂次突破病例高于≥3年,差异有统计学意义(x2=23.096,P<0.05).学生第2剂次突破病例高于幼托儿童,差异有统计学意义(x2=7.096,P<0.05).结论 接种第2剂次水痘疫苗出现的突破病例明显减少,建议在4~5岁接种第2剂次水痘疫苗.
Abstract
Objective To analyze the epidemiological characteristics of the breakthrough varicella in Yongchuan District and to provide reference for the prevention and control strategy of varicella.Methods Using descriptive epidemiological method,collecting varicella cases from 2020 to 2022 in Yongchuan District,the epidemiological characteristics of varicella cases under different vaccination doses were analyzed.Results There were 666 breakthrough cases out of 3 797 chickenpox cases.The number of reported cases was the highest in the group with no immunization history at 10 to<15 years old,and the number of breakthrough varicella was the highest in the group with 5 to<10 years old,the difference was statistically significant(x2=13.902,P<0.05).The number of second-dose breakthrough varicella in the age group of 5 to<10 years was higher than that in the age group of 10 to<15 years,the difference was statistically significant(x2=9.146,P<0.05).The number of second-dose breakthrough varicella in the group with less than 3 years between the onset time and the last vaccination was higher than that in the group with 3 years or more,the difference was statistically significant(x2=23.096,P<0.05).The second-dose breakthrough varicella in students were higher than those in preschool children,the difference was statistically significant(x2=7.096,P<0.05).Conclusion Inoculation with second-dose varicella vaccine can significantly reduce breakthrough varicella,and inoculation with second-dose varicella vaccine at 4-5 years of age is recommended.
关键词
水痘/突破病例/1剂次疫苗/2剂次疫苗/重庆Key words
varicella/breakthrough varicella/first-doses varicella vaccine/second-doses varicella vaccine/Chongqing引用本文复制引用
出版年
2024