摘要
目的 了解张家港市EV71疫苗接种率变化特征,掌握接种后不良反应报告情况,结合接种工作启动前后手足口病发病变化趋势,为EV71疫苗接种策略提供科学依据.方法 通过江苏省预防接种综合服务管理系统、国家免疫规划信息系统、国家疾病监测信息报告管理系统分别收集EV71疫苗实种剂次数、适龄儿童管理人数、EV71疫苗接种后不良反应报告数、手足口病发病数据,采用描述性流行病学方法呈现分布特征,运用卡方检验进行数据分析.结果 2017-2022年张家港市EV71疫苗首剂接种率分别为0.53％、3.49％、3.46％、4.38％、4.15％、4.56％,整体呈上升趋势;不良反应报告发生率17.40/10万针次;2018-2022年张家港市手足口病病原学分型中EV71占比(0.34％)较2013-2017年(20.77％)明显降低.结论 2017-2022年张家港市EV71疫苗接种工作稳步、安全、有效开展,建议今后继续加强EV71疫苗相关知识的宣传,提高疫苗接种率和接种依从性.
Abstract
Objective To understand the change characteristics of EV71 vaccination rate in Zhangjiagang and grasp the reporting of adverse reactions after vaccination,combined with the trend of the incidence of hand-foot-mouth disease(HFMD)before and after the vaccination,to provide scientific basis for EV71 vaccination strategy.Methods The number of live doses of EV71 vaccine,children of appropriate age,adverse reactions reported after EV71 vaccination and the incidence of HFMD were collected through Jiangsu Province Vaccination Integrated Service Management Information System,National Immunization Program Information System and National Disease Surveillance Information Reporting Management System.Descriptive epidemiological method was used to present distribution characteristics,and chi-square test was used for data analysis.Results From 2017 to 2022,the first dose vaccination rate of EV71 vaccine in Zhangjiagang was 0.53％,3.49％,3.46％,4.38％,4.15％and 4.56％respectively,and there was an upward trend.The reported incidence of adverse reactions was 17.40 per 10,0000 injections.From 2018 to 2022,the proportion of EV71(0.34％)in the pathogens of HFMD in Zhangjiagang was significantly lower than that in 2013-2017(20.77％).Conclusion The EV71 vaccination in Zhangjiagang from 2017 to 2022 was carried out steadily,safely and effectively.It is recommended that strengthen the dissemination of knowledge about EV71 vaccine,increase vaccination rate and adherence.
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万方数据