Investigation of an entry person infected with Omicron variant during quarantine period in Guangzhou
Objective Based on the analysis of a case infected with Omicron variant strain of SARS-CoV-2 in isolation period,the source and route of infection of the case during isolation period were identified,and corrective measures were proposed for the isolation hotel to reduce the risk of infection at the isolation point.Methods Through retrospective monitoring,field investigation,sampling verification,gene sequencing and other methods,a COVID-19 case found in Guangzhou City on the 22d of entry quarantine in January 2023 was investigated.Results According to the next-generation sequencing analysis,this case belonged to Omicron variant BA.1/21K,which had 62 mutation sites compared with Wuhan reference strain(NC045512),and shared all 62 mutation sites with the COVID-19 case in the adjacent room,and the two sequences were highly homologous.The two people lived next to each other for only 14 h,and there was no direct or indirect contact during the isolation period,the exhaust and drainage pipes between the two rooms were not connected.However,the on-site investigation found that the two rooms were not completely separated above the wall and ceilings,the two rooms were equipped with conditions for air exchange and gas circulation,resulted in accidental exposure and infection risk.Conclusion To convert a traditional hotel into an isolated hotel,it is necessary to check the potential risks caused by the building structure of the hotel room.
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