Whole genome sequencing analysis of imported SARS-CoV-2 at Chengdu port
Objective To analyze the whole genome sequence of imported severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)isolated at Chengdu port,and to understand the distribution of imported SARS-CoV-2 variants at Chengdu port.Methods Nasal and pharyngeal swab samples of 58 SARS-CoV-2 infected patients at Chengdu port from October 2022 to March 2023 were randomly selected,whole genome of SARS-CoV-2 was sequenced using the third-generation Nanopore sequencing platform,and the classification and coverage of Pangolin was determined using Baiyi whole genome analysis software system.The distribution of imported SARS-CoV-2 variants was analyzed.Results A total of 58 whole genome sequences of SARS-CoV-2 were obtained,of which 53 cases with sequence coverage greater than 99％were Omicron variants.The five most numerous variants were BA.5(21 strains,36.21％),XBB.l(9 strains,15.52％),BQ.1(7 strains,12.07％),BF.7(5 strains,8.62％),BA.2(3 strains,5.17％),which were consistent with the dominant strains in the world.Conclusion The imported SARS-CoV-2 variants distribution at Chengdu port was consistent with the global epidemic trend.
NETL
NSTL
万方数据
