Etiology,pathogen distribution and characteristics of 68 children with chronic cough
Objective To analyze the etiology,pathogen distribution and clinical characteristics of children with chronic cough in Deyu Medical Ma'anshan General Hospital and to provide evidence for diagnosis and treatment.Methods A total of 68 children with chronic cough admitted to Deyu Medical Ma'anshan General Hospital from May 2018 to May 2023 were randomly selected.Seven types of bacteria were detected by sputum culture,including Streptococcus pneumoniae,Klebsiella pneumoniae,Haemophilus influenzae,Escherichia coli,Pseudomonas aeruginosa,Staphylococcus aureus and Enterobacter cloacae.IgM of influenza virus,respiratory syncytial virus,Mycoplasma and Chlamydia were detected by Enzyme-linked immunosorbent assay.Results Among 68 children with chronic cough,15 had upper airway cough syndrome(U ACS),accounted for 22.06％.18 cases of variant asthma(CVA),accounted for 26.47％,27 cases had post-infectious cough(PIC),accounted for 39.71％.There were 6 cases(8.82％)of gastroesophageal reflux cough(GERC)and 2 cases(2.94％)of eosinophilic bronchitis(EB).There was no significant difference in gender and age between children with different etiologies(P＞0.05).Among the 68 children,pathogens were detected positive in 52 cases,of which 15 cases were infected by single bacterium,accounted for 28.85％.19 cases of single Mycoplasma infection,accounted for 36.54％.There were 2 cases of single virus infection,accounted for 3.85％,four cases of single Chlamydia infection,accounted for 7.69％,12 cases were mixed infection,accounted for 23.07％.The main clinical features were dry cough,morning cough and infection,accounted for 55.88％,52.94％and 76.47％,respectively.Conclusion PIC,UACS and CVA were the most common causes of chronic cough in children in Deyu Medical Ma'anshan General Hospital.Bacteria and Mycoplasma infection were the main pathogens.Cough characteristics were dry cough,morning cough and infection related.
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