摘要
目的 分析德驭医疗马鞍山总医院儿童慢性咳嗽的病因、病原体分布及临床特征,为诊疗提供依据.方法 随机选取德驭医疗马鞍山总医院2018年5月-2023年5月收治的68例慢性咳嗽儿童,通过痰培养检测7种细菌,包括肺炎链球菌、肺炎克雷伯菌、流感嗜血杆菌、大肠埃希菌、铜绿假单胞菌、金黄色葡萄球菌、阴沟肠杆菌;用酶联吸附法检测流感病毒、呼吸道合胞病毒和支原体、衣原体IgM.结果 68例慢咳嗽患儿中上气道咳嗽综合征(UACS)15例,占22.06％;变异性哮喘(CVA)18例,占26.47％;感染后咳嗽(PIC)27例,占39.71％;胃食管反流性咳嗽(GERC)6例,占8.82％,嗜酸粒细胞性支气管炎(EB)2例,占2.94％.不同病因患儿性别、年龄差异无统计学意义(P＞0.05).68例患儿中有52例检出病原体,其中单一细菌感染15例,占28.85％;单一支原体感染19例,占36.54％;单一病毒感染2例,占3.85％;单一衣原体感染4例,占7.69％;混合感染12例,占23.07％;患儿临床特征中以干咳、晨咳、感染相关为主,分别占55.88％、52.94％、76.47％.结论 德驭医疗马鞍山总医院慢性咳嗽患儿临床病因以PIC、UACS、CVA较常见,病原体以细菌和支原体感染为主,咳嗽特征以干咳、晨咳、感染相关为主.
Abstract
Objective To analyze the etiology,pathogen distribution and clinical characteristics of children with chronic cough in Deyu Medical Ma'anshan General Hospital and to provide evidence for diagnosis and treatment.Methods A total of 68 children with chronic cough admitted to Deyu Medical Ma'anshan General Hospital from May 2018 to May 2023 were randomly selected.Seven types of bacteria were detected by sputum culture,including Streptococcus pneumoniae,Klebsiella pneumoniae,Haemophilus influenzae,Escherichia coli,Pseudomonas aeruginosa,Staphylococcus aureus and Enterobacter cloacae.IgM of influenza virus,respiratory syncytial virus,Mycoplasma and Chlamydia were detected by Enzyme-linked immunosorbent assay.Results Among 68 children with chronic cough,15 had upper airway cough syndrome(U ACS),accounted for 22.06％.18 cases of variant asthma(CVA),accounted for 26.47％,27 cases had post-infectious cough(PIC),accounted for 39.71％.There were 6 cases(8.82％)of gastroesophageal reflux cough(GERC)and 2 cases(2.94％)of eosinophilic bronchitis(EB).There was no significant difference in gender and age between children with different etiologies(P＞0.05).Among the 68 children,pathogens were detected positive in 52 cases,of which 15 cases were infected by single bacterium,accounted for 28.85％.19 cases of single Mycoplasma infection,accounted for 36.54％.There were 2 cases of single virus infection,accounted for 3.85％,four cases of single Chlamydia infection,accounted for 7.69％,12 cases were mixed infection,accounted for 23.07％.The main clinical features were dry cough,morning cough and infection,accounted for 55.88％,52.94％and 76.47％,respectively.Conclusion PIC,UACS and CVA were the most common causes of chronic cough in children in Deyu Medical Ma'anshan General Hospital.Bacteria and Mycoplasma infection were the main pathogens.Cough characteristics were dry cough,morning cough and infection related.
NETL
NSTL
万方数据