Pathogen and clinical symptom analysis of viral pneumonia in children
Objective To explore the distribution of common viral pneumonia in children,and analyze the correlation between clinical symptoms,signs and pathogenic distribution,to provide a basis for clinical diagnosis and treatment.Methods A total of 200 children with viral pneumonia treated at Beijing Friendship Hospital from January 2019 to January 2023 were selected,and enzyme-linked immunosorbent assay(ELISA)was used to quantitatively detect 5 kinds of respiratory viruses,the differences in pathogen distribution were compared.The differences in clinical symptoms and signs of children with different infection types were analyzed.Results There were 156 cases of single infection,accounted for 78.00％,and 44 cases of mixed infection,accounted for 22.00％.Single infection was mainly caused by respiratory syncytial virus(RSV),accounted for 37.18％of single infections.Mixed infections were mainly caused by influenza virus(IFV)and parainfluenza virus(PIV),accounted for 47.73％of mixed infections.The mixed infection rate of children aged ≤ 3 years was 43.94％,significantly higher than that of children aged 3-7 years and＞7 years(P＜0.05).The RSV infection rate in children aged ≤ 3 years was 59.09％,significantly higher than that in children aged 3-7 years and＞7 years(P＜0.05).The IFV infection rate in children over 7 years old was 20.00％,significantly lower than that in children ≤3 years old and 3-7 years old(P＜0.05).The proportion of PIV in children aged over 7 years old was 47.27％,significantly higher than that in children aged ≤3 years and 3-7 years old(P＜0.05).There was no statistically significant difference in the infection rates of adenovirus(ADV)and cytomegalovirus(CMV)among children of different ages(P＞0.05),There was no statistically significant difference in the infection types and RSV,IFV,PIV,ADV and CMV infection rates among children of different genders(P＞0.05).The proportions of fever and wet rales in children with mixed infections were 95.45％and 93.18％,respectively,which were significantly higher than those in patients with single infections(P＜0.05).There was no statistically significant difference in cough,asthma,and wheezing between children with single infections and those with mixed infections(P＞0.05).There was no statistically significant difference in clinical symptoms and signs caused by RSV,IFV,PIV,ADV and CMV infections(P＞0.05).Conclusion Children viral pneumonia was mainly caused by RSV,IFV infections.There were differences in clinical symptoms and signs between children with single infection and mixed infection,which was helpful for early diagnosis.
ChildViral pneumoniaPathogenologyClinical symptom and sign
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