首页|鲍曼不动杆菌无菌体液感染患者归因危险度多中心回顾性队列研究

鲍曼不动杆菌无菌体液感染患者归因危险度多中心回顾性队列研究

扫码查看
原文链接
  • 国家科技期刊平台
  • NETL
  • NSTL
  • 万方数据
  • 维普
目的 调查重症患者感染鲍曼不动杆菌(AB)后的归因危险度(AR)。方法 围绕成人重症监护病房(ICU)患者开展多中心回顾性队列研究。以各中心从无菌体液中分离出AB且确认AB感染患者为感染组，以同期、同一 ICU、相似的急性生理与慢性健康评分Ⅱ(APACHE Ⅱ)评分(±5分)和入住ICU的主要诊断为匹配条件，按1:2比例选取未感染AB患者作为非感染组，计算AR。结果 AB无菌体液感染患者住院病死率为33。3％，非感染组患者为23。1％，两组数据比较，差异无统计学意义(P=0。069)，AR为10。2％(95％CI:-2。3％～22。8％)。血、脑脊液等标本来源的感染组和非感染组患者病死率比较，差异无统计学意义(P＞0。05)。主要诊断为肺部感染的重症患者感染AB后AR最高，但感染组和非感染组患者病死率比较，差异无统计学意义(P＞0。05)，其他诊断分类同样如此。结论 重症患者AB感染预后被严重高估，但ICU仍应针对AB进行积极医院感染控制。
A multicenter retrospective cohort study on the attributable risk of patients with Acinetobacter baumannii sterile body fluid infection
Objective To investigate the attributable risk(AR)of Acinetobacter baumannii(AB)infection in criti-cally ill patients.Methods A multicenter retrospective cohort study was conducted among adult patients in inten-sive care unit(ICU).Patients with AB isolated from sterile body fluid and confirmed with AB infection in each cen-ter were selected as the infected group.According to the matching criteria that patients should be from the same pe-riod,in the same ICU,as well as with similar APACHE Ⅱ score(±5 points)and primary diagnosis,patients who did not infect with AB were selected as the non-infected group in a 1:2 ratio.The AR was calculated.Results The in-hospital mortality of patients with AB infection in sterile body fluid was 33.3％,and that of non-infected group was 23.1％,with no statistically significant difference between the two groups(P=0.069).The AR was 10.2％(95％CI:-2.3％-22.8％).There is no statistically significant difference in mortality between non-infected pa-tients and infected patients from whose blood,cerebrospinal fluid and other specimen sources AB were isolated(P＞0.05).After infected with AB,critically ill patients with the major diagnosis of pulmonary infection had the high-est AR.There was no statistically significant difference in mortality between patients in the infected and non-infec-ted groups(P＞0.05),or between other diagnostic classifications.Conclusion The prognosis of AB infection in critically ill patients is highly overestimated,but active healthcare-associated infection control for AB in the ICU should still be carried out.

Acinetobacter baumanniiattributable riskprognosissterile body fluidbloodmulticenter cohort study

何磊、姜道彬、刘丁、郑小芳、邱荷语、吴淑梅、吴晓英、崔金兰、谢首佳、夏琴、何莉、刘晞照、舒昌惠、李荣琴、陶红英、陈泽芬

展开 >

重庆市大足区人民医院感染控制科,重庆 402360

陆军军医大学陆军特色医学中心疾病预防控制科,重庆 400042

重庆大学附属涪陵医院感染管理科,重庆 408099

重庆医科大学附属永川医院感染管理科,重庆 402160

重庆市秀山县人民医院感染管理科,重庆 409999

重庆市开州区人民医院感染管理科,重庆 405400

重庆市南川区人民医院院感科,重庆 408400

成都市蒲江县人民医院感染管理科,四川成都 611630

重庆大学附属三峡医院感染管理科,重庆 404000

重庆市璧山区人民医院感染管理科,重庆 402760

重庆市綦江区人民医院感染管理科,重庆 401420

重庆市长寿区人民医院感染管理科,重庆 401220

重庆大学附属江津医院感染管理科,重庆 402260

展开 >

鲍曼不动杆菌 归因危险度 预后 无菌体液 血 多中心队列研究

重庆市卫生计生委重点项目

20141024

2024

10.12138/j.issn.1671-9638.20243007

中国感染控制杂志
中南大学

中国感染控制杂志

CSTPCD北大核心
影响因子：2.112
ISSN：1671-9638
年,卷(期)：2024.23(1)
  • 38