Change in antimicrobial resistance of Granulicatella adiacens isolated from blood specimens,CARSS,2014-2021
Objective To understand the change in antimicrobial resistance of Granulicatella adiacens(G.adia-cens)clinically isolated from blood specimens in China,provide basis for clinical treatment.Methods Surveillance on antimicrobial resistance of bacteria was carried out according to the requirements of China Antimicrobial Resis-tance Surveillance System(CARSS).Antimicrobial susceptibility testing results of G.adiacens isolated from blood specimens of member units of CARSS in 2014-2021 were analyzed based on standard of American Clinical and La-boratory Standards Institute(CLSI).Results 83-152 strains of G.adiacens were isolated from blood specimens from member units of CARSS each year from 2014 to 2021,there was a gradual increasing trend after 2017.The susceptibility rates of G.adiacens isolated from blood specimens to vancomycin and meropenem were 100%and 93.7%respectively,to ceftriaxone,cefotaxime and cefepime were about 90%,to levofloxacin,penicillin,erythromycin and clindamycin were 82.8%,65.0%,32.7%and 46.8%,respectively.From 2014 to 2021,susceptibility rates of G.adiacens to partial antimicrobial agents increased to varying degrees,but to cefepime and meropenem decreased.Conclusion The number of G.adiacens isolated from blood specimens showed a rising trend,G.adiacens exhibits varying degrees of resistance to penicillin,cephalosporins,carbapenems,fluoroquinolones and macrolides,but no vancomycin-resistant strain was found.
Granulicatella adiacensantimicrobial agentantimicrobial resistanceChina Antimicrobial Resis-tance Surveillance System