首页|湖南省细菌耐药监测网2012-2021年葡萄球菌属细菌耐药性监测报告

湖南省细菌耐药监测网2012-2021年葡萄球菌属细菌耐药性监测报告

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目的 了解2012-2021年湖南省临床标本分离病原菌中葡萄球菌属的分布及耐药性,为临床抗菌药物合理应用,以及制定和评价抗菌药物临床应用管理政策提供科学依据。方法 按照全国细菌耐药监测网(CRASS)技术方案,应用WHONET 5。6软件对2012-2021年湖南省细菌耐药监测网上报的葡萄球菌属耐药性进行分析。结果 2012-2021年,葡萄球菌属中分离稳居前4位的细菌分别为金黄色葡萄球菌、表皮葡萄球菌、溶血葡萄球菌和人葡萄球菌。葡萄球菌属标本来源以痰、血、分泌物、伤口脓液和尿为主,其中痰标本占25。4%~31。8%,血标本占21。9%~27。8%。在所有临床分离的细菌中,葡萄球菌属占比为15。5%~22。4%,呈现缓慢下降的趋势。10年来,耐甲氧西林金黄色葡萄球菌(MRSA)检出率有所下降,从35。1%下降至24。8%,同时耐甲氧西林凝固酶阴性葡萄球菌(MRCNS)检出率有所上升,但是仍保持在70%以内。葡萄球菌属细菌对万古霉素、替考拉宁和利奈唑胺的敏感率为100%。结论 湖南省临床分离葡萄球菌属细菌中,MRSA检出率有所下降,未发现对万古霉素、替考拉宁和利奈唑胺耐药的葡萄球菌属细菌。应继续加强抗菌药物合理应用的管理及医院感染防控,做好细菌耐药监测工作。
Antimicrobial resistance of Staphylococcus spp.:surveillance report from Hunan Province Antimicrobial Resistance Surveillance System,2012-2021
Objective To understand the distribution and antimicrobial resistance of Staphylococcus spp.isolated from clinical specimens in Hunan Province from 2012 to 2021,provide scientific basis for rational clinical antimicro-bial use as well as the formulation and evaluation of management policies for clinical antimicrobial use.Methods According to China Antimicrobial Resistance Surveillance System(CARSS)technical scheme,antimicrobial resis-tance of Staphylococcus spp.reported by Hunan Province Antimicrobial Resistance Surveillance System in 2012-2021 was analyzed with WHONET 5.6 software.Results From 2012 to 2021,the top 4 isolated Staphylococcus were Staphylococcus aureus,Staphylococcus epidermidis,Staphylococcus haemolyticus and Staphylococcus homi-nis.Staphylococcus spp.were mainly isolated from specimens of sputum,blood,secretion,wound pus,and urine.Sputum and blood specimens accounting for 25.4%-31.8%and 21.9%-27.8%,respectively.Among all clinica-lly isolated bacteria,Staphylococcus spp.accounted for 15.5%-22.4%,showing a slowly downward trend.In the past 10 years,detection rates of methicillin-resistant Staphylococcus aureus(MRSA)decreased from 35.1%to 24.8%,while detection rates of methicillin-resistant coagulase negative Staphylococcus(MRCNS)increased,but were lower than 70%.Susceptibility rates of Staphylococcus spp.to vancomycin,teicolanin and linezolid were 100%.Conclusion Among clinically isolated Staphylococcus spp.in Hunan Province,the detection rate of MRSA has de-creased.Vancomycin-,teicoplanin-and linezolid-resistant Staphylococcus spp.were not found.Management of ra-tional use of antimicrobial agents as well as prevention and control of healthcare-associated infection should be strengthened continuously,and antimicrobial resistance surveillance should be conducted well.

antimicrobial agentStaphylococcus spp.antimicrobial resistancesurveillancemultidrug-resistant organismHunan Province Antimicrobial Resistance Surveillance System

邬靖敏、沈晖、伍勇、陈丽华、付陈超、李晨、李艳明、刘君、宁兴旺、石国民、杨怀德、袁红霞、郑铭、任南、吴安华、黄勋、胡金伟、曾翠

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长沙市第一医院检验科,湖南长沙 410005

中南大学湘雅三医院检验科,湖南长沙 410013

中南大学湘雅医院医院感染控制中心,湖南长沙 410008

湖南省细菌耐药监测网办公室,湖南长沙 410008

国家老年疾病临床医学研究中心(湘雅医院),湖南长沙 410008

浏阳市中医医院检验科,湖南浏阳 410300

中南大学湘雅医院检验科,湖南长沙 410008

湘潭市中心医院检验科,湖南湘潭 411100

湖南中医药大学第一附属医院医学检验与病理中心,湖南长沙 410011

长沙市中心医院检验科,湖南长沙 410004

张家界市人民医院检验科,湖南张家界 427000

郴州市第一人民医院检验医学中心,湖南郴州 423000

湖南省医院感染管理质量控制中心,湖南长沙 410008

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抗菌药物 葡萄球菌属 耐药性 监测 多重耐药菌 湖南省细菌耐药监测网

长沙市卫生健康委科研立项项目

KJ-B2023050

2024

中国感染控制杂志
中南大学

中国感染控制杂志

CSTPCD北大核心
影响因子:2.112
ISSN:1671-9638
年,卷(期):2024.23(4)
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