Antimicrobial resistance of Staphylococcus spp.:surveillance report from Hunan Province Antimicrobial Resistance Surveillance System,2012-2021
Objective To understand the distribution and antimicrobial resistance of Staphylococcus spp.isolated from clinical specimens in Hunan Province from 2012 to 2021,provide scientific basis for rational clinical antimicro-bial use as well as the formulation and evaluation of management policies for clinical antimicrobial use.Methods According to China Antimicrobial Resistance Surveillance System(CARSS)technical scheme,antimicrobial resis-tance of Staphylococcus spp.reported by Hunan Province Antimicrobial Resistance Surveillance System in 2012-2021 was analyzed with WHONET 5.6 software.Results From 2012 to 2021,the top 4 isolated Staphylococcus were Staphylococcus aureus,Staphylococcus epidermidis,Staphylococcus haemolyticus and Staphylococcus homi-nis.Staphylococcus spp.were mainly isolated from specimens of sputum,blood,secretion,wound pus,and urine.Sputum and blood specimens accounting for 25.4%-31.8%and 21.9%-27.8%,respectively.Among all clinica-lly isolated bacteria,Staphylococcus spp.accounted for 15.5%-22.4%,showing a slowly downward trend.In the past 10 years,detection rates of methicillin-resistant Staphylococcus aureus(MRSA)decreased from 35.1%to 24.8%,while detection rates of methicillin-resistant coagulase negative Staphylococcus(MRCNS)increased,but were lower than 70%.Susceptibility rates of Staphylococcus spp.to vancomycin,teicolanin and linezolid were 100%.Conclusion Among clinically isolated Staphylococcus spp.in Hunan Province,the detection rate of MRSA has de-creased.Vancomycin-,teicoplanin-and linezolid-resistant Staphylococcus spp.were not found.Management of ra-tional use of antimicrobial agents as well as prevention and control of healthcare-associated infection should be strengthened continuously,and antimicrobial resistance surveillance should be conducted well.
antimicrobial agentStaphylococcus spp.antimicrobial resistancesurveillancemultidrug-resistant organismHunan Province Antimicrobial Resistance Surveillance System