首页|非O1/O139群霍乱弧菌致肝硬化失代偿期患者血流感染1例

非O1/O139群霍乱弧菌致肝硬化失代偿期患者血流感染1例

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患者,男性,58岁,乙型肝炎后肝硬化失代偿期、2型糖尿病12年,近1个月再发腹胀、水肿,尿少入院。住院期间患者寒战、发热,取血标本进行培养,选用头孢哌酮/舒巴坦经验性抗感染治疗。确诊非O1/O139霍乱弧菌引起的血流感染,药敏试验提示头孢哌酮/舒巴坦敏感后,继续使用当前药物,头孢哌酮/舒巴坦由3 g q12h改为3 gq8h治疗。10 d后患者无发热,血培养和粪便霍乱弧菌培养阴性,好转出院。
Bloodstream infection caused by non-O1/O139 Vibrio cholerae in patient with decompensated cirrhosis:one case report
A 58-year-old male patient with decompensated cirrhosis after hepatitis B and type n diabetes for 12 years was admitted to hospital due to abdominal distension,edema and oliguria in recent one month.During hospi-talization period,the patient experienced chills and fever,blood specimens were taken for culture,empirical anti-in-fection treatment with cefoperazone/sulbactam was given.The diagnosis of bloodstream infection caused by non-O1/O139 Vibrio cholerae was confirmed,antimicrobial susceptibility testing indicated that cefoperazone/sulbactam was sensitive,current antimicrobial agent was continued,cefoperazone/sulbactam 3 g q12h was changed to 3 g q8h treatment.After 10 days,the patient had no fever,blood and fecal cultures were negative for Vibrio cholerae,con-dition was improved and patient was discharged from the hospital.

liver cirrhosisnon-O1 groupnon-O139 groupVibrio choleraesepticemia

李红森、赵越、张妮

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贵港市妇幼保健院检验科,广西贵港 537100

南方医科大学附属广东省人民医院/广东省医学科学院检验科,广东广州 510080

肝硬化 非O1群 非O139群 霍乱弧菌 败血症

2024

中国感染控制杂志
中南大学

中国感染控制杂志

CSTPCD北大核心
影响因子:2.112
ISSN:1671-9638
年,卷(期):2024.23(4)
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