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结核硬脂酸棒状杆菌引起脐尿管感染1例

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报告1例患者因脐部疼痛入院,患者脐部脓性分泌物标本革兰染色可见短小阳性球杆菌,同时对分离菌株采用基质辅助激光解吸电离飞行时间质谱(MALDI-TOF MS)技术进行鉴定和16S rRNA检测,并进行体外药敏试验。革兰染色、MALDI-TOF MS鉴定和16S rRNA检测结果均为结核硬脂酸棒状杆菌。药敏结果提示该菌对青霉素、头孢曲松、头孢吡肟、美罗培南、万古霉素、达托霉素、利奈唑胺、复方磺胺甲唑、氨苄西林、庆大霉素、四环素均敏感。微生物的形态学涂片有助于结核硬脂酸棒状杆菌的鉴别,MALDI-TOF MS对于快速鉴定该菌种是必要的,药敏试验也可以为临床该菌感染的经验性治疗提供一定的帮助。
A case of urachal infection caused by Corynebacterium tuberculostearicum
A patient was admitted to hospital due to umbilical pain.Gram-staining presented short,positive coc-cobacillus in the purulent secretions from the umbilical cord of the patient.Meanwhile,matrix-assisted laser desorp-tion/ionization time-of-flight mass spectrometry(MALDI-TOF MS),16S rRNA detection,and in vitro antimicro-bial susceptibility testing were performed on the isolated strains.Corynebacterium tuberculostearicum was identified by Gram-staining,MALDI-TOF MS and 16S rRNA.Antimicrobial susceptibility testing results showed that the strain was sensitive to penicillin,ceftriaxone,cefepime,meropenem,vancomycin,daptomycin,linezolid,compound sulfamethoxazole,ampicillin,gentamicin and tetracycline.Smear of microorganisms is helpful for the identification of Corynebacterium tuberculostearicum morphology,and MALDI-TOF MS is necessary for rapid identification of strains.Antimicrobial susceptibility testing can also assist the empirical treatment for infection due to this strain.

Corynebacterium tuberculostearicumurachusinfection

王崇圳、麦吉仁、钟山、许丽霞、王立程、符晓莹、李欢、黎元莉、陈东科

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三亚市人民医院检验科/中心实验室,海南三亚 572000

三亚市人民医院泌尿外科,海南三亚 572000

结核硬脂酸棒状杆菌 脐尿管 感染

2024

中国感染控制杂志
中南大学

中国感染控制杂志

CSTPCD北大核心
影响因子:2.112
ISSN:1671-9638
年,卷(期):2024.23(12)