Clinical analysis of 21 cases of single-level lumbar brucellosis spondylitis treated by OLIF operation
Objective To explore the clinical effect of oblique lumbar interbody fusion(OLIF)through oblique lateral approach in the treatment of single-level lumbar brucellosis spondylitis.Methods From January 2013 to January 2022,the clinical data of 21 cases of single-level lumbar brucellosis spondylitis treated by OLIF in our hospital were retrospectively analyzed.The operation time,intraoperative blood loss,postoperative drainage,drainage time,hospitalization,erythrocyte sedimentation rate(ESR)C-reactive protein(CRP),interleukin-6(IL-6)and other infection indexes,visual analogue scale of pain(VAS)and Japanese Orthopaedic Association(JOA)before operation,3 months after operation and at the last follow-up were analyzed.Bridwell bone grafting standard and evaluation of improved MacNab at the last follow-up were observed.Results All patients were followed up for 20-25 months,with an average of 22 months.The operation time was 170-280 min,with an average of(229.47±56.45)min;the intraoperative blood loss was 30-150 ml,with an average of(71.42±32.44)ml;the postoperative drainage was 30-150 ml,with an average of(63.09±30.18)ml;drainage time was 1-5 days,with an average of(2.85±1.31)days.The hospitalization ranged from 7 to 16 days,with an average of(9.80±2.46)days.At the last follow-up,ESR,CRP and IL-6 infection indexes of all patients returned to normal.The results of RBPT(Tiger Red Slide Agglutination Test)and SAT(Tube Agglutination Test)were all negative after 6 months of oral anti-Brucella drugs.The pain and function of the patient were obviously improved 3 months after operation,and the VAS and JOA scores were statistically different from those before operation(P<0.05).According to Bridwell bone grafting standard,all patients'bone grafting healed completely,and no related complications occurred.At the last follow-up,19 cases were"excellent"and 2 cases were"good",and the excellent and good rate was 100%.Conclusions On the basis of standardized anti-brucellosis drug therapy,OLIF operation has the advantages of less surgical trauma,less bleeding,less drainage,less postoperative complications and quick recovery.It is a safe and effective surgical approach in the treatment of lumbar brucellosis.