首页|21例经斜外侧入路腰椎椎体间融合术治疗单节段腰椎布氏杆菌脊柱炎的疗效分析

21例经斜外侧入路腰椎椎体间融合术治疗单节段腰椎布氏杆菌脊柱炎的疗效分析

扫码查看
目的 探讨斜外侧入路腰椎椎体间融合术(oblique lumbar interbody fusion,OLIF)治疗单节段腰椎布氏杆菌性脊柱炎的临床疗效.方法 回顾分析 2013 年 1 月至 2022 年 1 月,于我院行 OLIF 治疗的21 例单节段腰椎布氏杆菌脊柱炎患者的病例资料,分析患者手术时间、术中出血量、术后引流量、引流时间、住院天数,术前、术后 3 个月及末次随访时的红细胞沉降率(erythrocyte sedimentation rate,ESR)、C 反应蛋白(C-reactive protein,CRP)、白介素-6(interleukin-6,IL-6)等感染指标变化,疼痛视觉模拟评分(visual analogue scale,VAS)和日本骨科协会(Japanese Orthopaedic Association,JOA);Bridwell 植骨标准及末次随访时改良的 MacNab 疗效评估.结果 所有患者均获得 20~25 个月随访,平均 22 个月,手术时间 170~280 min,平均(229.47±56.45)min、术中出血量 30~150 ml,平均(71.42±32.44)ml;术后引流量 30~150 ml,平均(63.09±30.18)ml;引流时间 1~5 天,平均(2.85±1.31)天;住院天数 7~16 天,平均(9.80±2.46)天.末次随访时,所有患者 ESR、CRP、IL-6 感染指标均恢复正常.出院口服抗布氏杆菌药物,6 个月后及末次随访时虎红平板凝集试验(Rose-Bengal plate agglutination test,RBPT)、试管凝集试验(slide agglutination test,SAT)结果均阴性,术后 3 个月患者疼痛及功能已明显改善,术后 3 个月及末次随访时,VAS 评分、JOA 评分同术前相比差异有统计学意义(P<0.05).根据 Bridwell 植骨标准,所有患者植骨均完全愈合,未见相关并发症出现.末次随访时改良 MacNab 评分,19 例"优",2 例"良",优良率达 100%.结论 在规范化抗布氏杆菌脊柱炎药物治疗的基础上,OLIF 具有手术创伤小、出血量少、引流量低、术后并发症少、恢复快等优点,在治疗腰椎布氏杆菌脊柱炎方面,是一种安全、有效的手术入路.
Clinical analysis of 21 cases of single-level lumbar brucellosis spondylitis treated by OLIF operation
Objective To explore the clinical effect of oblique lumbar interbody fusion(OLIF)through oblique lateral approach in the treatment of single-level lumbar brucellosis spondylitis.Methods From January 2013 to January 2022,the clinical data of 21 cases of single-level lumbar brucellosis spondylitis treated by OLIF in our hospital were retrospectively analyzed.The operation time,intraoperative blood loss,postoperative drainage,drainage time,hospitalization,erythrocyte sedimentation rate(ESR)C-reactive protein(CRP),interleukin-6(IL-6)and other infection indexes,visual analogue scale of pain(VAS)and Japanese Orthopaedic Association(JOA)before operation,3 months after operation and at the last follow-up were analyzed.Bridwell bone grafting standard and evaluation of improved MacNab at the last follow-up were observed.Results All patients were followed up for 20-25 months,with an average of 22 months.The operation time was 170-280 min,with an average of(229.47±56.45)min;the intraoperative blood loss was 30-150 ml,with an average of(71.42±32.44)ml;the postoperative drainage was 30-150 ml,with an average of(63.09±30.18)ml;drainage time was 1-5 days,with an average of(2.85±1.31)days.The hospitalization ranged from 7 to 16 days,with an average of(9.80±2.46)days.At the last follow-up,ESR,CRP and IL-6 infection indexes of all patients returned to normal.The results of RBPT(Tiger Red Slide Agglutination Test)and SAT(Tube Agglutination Test)were all negative after 6 months of oral anti-Brucella drugs.The pain and function of the patient were obviously improved 3 months after operation,and the VAS and JOA scores were statistically different from those before operation(P<0.05).According to Bridwell bone grafting standard,all patients'bone grafting healed completely,and no related complications occurred.At the last follow-up,19 cases were"excellent"and 2 cases were"good",and the excellent and good rate was 100%.Conclusions On the basis of standardized anti-brucellosis drug therapy,OLIF operation has the advantages of less surgical trauma,less bleeding,less drainage,less postoperative complications and quick recovery.It is a safe and effective surgical approach in the treatment of lumbar brucellosis.

BrucellosisSpondylitisMinimally invasive surgical procedures

张凯、刘华、李旭升、李松凯

展开 >

730000 兰州,甘肃中医药大学第一临床医学院

730050 兰州,中国人民解放军联勤保障部队第九四〇医院脊柱外科

布鲁杆菌病 脊柱炎 最小侵入性外科手术

甘肃省科技计划甘肃省卫生健康行业科研项目

21YF1FA179GSWSKY2020-05

2024

中国骨与关节杂志
中国医疗保健国际交流促进会,北京中科康辰骨关节伤病研究所

中国骨与关节杂志

CSTPCD
影响因子:0.665
ISSN:2095-252X
年,卷(期):2024.13(1)
  • 1
  • 4