Perioperative use of aspirin in surgical treatment of lumbar spinal stenosis with posterior short-segment fusion:a case-control study
Objective To investigate the continuous use of aspirin in surgical treatment of lumbar spinal stenosis with posterior short segment fusions among patients with risks of vascular events.Methods Data of 92 patients diagnosed as lumbar spinal stenosis with risks of vascular accidents were collected from September 2018 to December 2021 in our center.All were treated with no more than 3 segmental fusions.Patients were divided into the aspirin group(perioperative use of aspirin,n = 46)and control group(no perioperative use of aspirin,n = 46).The basic information,intraoperative blood loss,blood transfusion rate,complications and follow-up results of the two groups were compared and analyzed.Results There were no significant differences in population and surgical data between the two groups.The mean intraoperative blood loss of the aspirin group(302.3±121.7)ml was higher than that of control group(253.6±126.4)ml,but the differences were not statistically significant(P = 0.603).There were no significant differences in total blood loss between the two groups[(156.9±89.8)ml in the aspirin group,(130.5±74.6)ml in the control group](P = 0.128).The Hct of drainage fluid in the aspirin group was(13.9±4.1)%on the second day after operation,which was significantly higher than that in the control group(10.1±5.7)%(P = 0.31).The blood loss on day 2 after operation in the aspirin group(35.7±22.2)ml was significantly higher than that in the control group(21.0±18.3)ml(P = 0.010).No patients in both groups required allogeneic blood transfusion perioperatively.No vascular accident,incision infection or intraspinal hematoma occurred during hospitalization and 3 months after operation in both groups.No aspirin-related adverse drug reactions occurred in the aspirin group.Conclusions Continuous use of aspirin in posterior lumbar surgeries with fusion of no more than 3 levels does not increase perioperative blood loss,transfusion rate or drainage tube placement.It is recommended for patients with risks of vascular events.
NETL
NSTL
万方数据
维普
