首页|髌上与髌下髓内钉治疗成人胫骨干骨折的Meta分析

髌上与髌下髓内钉治疗成人胫骨干骨折的Meta分析

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目的 分析髌下(infrapatellar,IP)技术和髌上(suprapatellar,SP)技术治疗成人胫骨骨折的疗效.方法 在这项符合 PRISMA 标准的系统综述和 Meta 分析中,从 2012 年 1 月至 2022 年 11 月,共检索了 7 个数据库,包含中国知网、维普科技期刊数据库、万方数据库、中国生物医学文献数据库、PubMed、Embase 和 Cochrane Library 数据库,检索了涉及 IP 和 SP 髓内钉治疗胫骨骨折对比的随机对照试验(randomized controlled trial,RCT).使用预先设计的检索策略进行检索,并通过 Cochrane 协作工具对所有合格的文献进行方法学质量的严格评估.提取术中透视次数、术中出血量、手术时间、住院天数、骨折愈合时间、HSS 评分、Lysholm 评分、疼痛视觉模拟评分(visual analogue scale,VAS)、膝关节伸屈活动度(range of motion,ROM)、切口感染率及再手术率,通过 Rview Manager 5.3 软件进行数据分析.结果 共纳入 12 篇研究,纳入患者的总数为 874 例,其中 SP 组 440 例,IP 组 434 例.结果的稳定与可靠主要通过敏感性分析进行评价,Meta 分析是否发表偏倚则通过发表偏倚检测来评定.结果显示:SP 组术中透视次数短于 IP 组(MD =-13.61,95%CI:-15.13~-12.09,P<0.000 01);SP 组的手术时间显著低于 IP 组(MD =-2.30,95%CI:-3.44~-1.16,P<0.0001);与髌下入路对比后,发现髌上入路手术的患者可获得更高的 Lysholm 评分(MD = 7.66,95%CI:6.25~9.07,P<0.000 01);SP 组的 HSS 评分显著高于 IP 组(MD = 6.47,95%CI:4.69~8.25,P<0.000 01);SP 组的 VAS 评分显著低于 IP 组(MD =-0.67,95%CI:-0.98~-0.35,P<0.0001);SP 组的 ROM 显著大于IP 组(MD = 2.50,95%CI:0.70~4.30,P = 0.006);两种手术方式的再手术率、切口感染率、骨折愈合时间、术中出血、住院天数比较,差异均无统计学意义(P>0.05).结论 髓内钉 SP 入路治疗成人胫骨骨折能显著减少术中透视次数及手术时间,且与膝关节术后疼痛评分降低和功能预后改善密切相关.
Meta-analysis of suprapatellar and infrapatellar intramedullary nails in the treatment of adult tibial shaft fractures
Objective To analyze the efficacy of infrapatellar(IP)and suprapatellar(SP)techniques in the treatment of adult tibial fractures.Methods In this systematic review and meta-analysis that meets the PRISMA standard,a total of 7 databases were searched from January 2012 to November 2022,including China National Knowledge Infrastructure,VIP Technology Journal Database,Wanfang Database,China Biomedical Literature Database,Pubmed,Embase,and Cochrane Library Database.Randomized controlled trials(RCTs)involving the comparison of IP and SP intramedullary nails for the treatment of tibial fractures were searched.Use a pre-designed retrieval strategy for retrieval and evaluate the methodological quality of all qualified literature through the Cochrane collaborative tool.Extract intraoperative fluoroscopy frequency,intraoperative bleeding volume,surgical time,hospital stay,fracture healing time,HSS score,Lysholm score,visual analog scale(VAS)of pain,range of motion(ROM)of knee joint,incision infection rate,and reoperation rate.The data were analyzed using Rview Manager 5.3 software.Results A total of 12 studies were analyzed(874 patients),including 440 in the SP group and 434 in the IP group.The stability and reliability of the results were mainly evaluated through sensitivity analysis,while the publication bias of meta-analysis was evaluated through publication bias detection.The results showed that the frequency of intraoperative fluoroscopy in SP group was lower than that in IP group(MD =-13.61,95%CI-15.13-12.09,P<0.000 01);The operation time in SP group was significantly shorter than that in IP group(MD =-2.30,95%CI-3.44--1.16,P<0.0001);Compared with the infrapatellar approach,the patients with suprapatellar approach could obtain higher Lysholm score(MD = 7.66,95%CI 6.25-9.07,P<0.000 01);The HSS score of SP group was significantly higher than that of IP group(MD = 6.47,95%CI 4.69-8.25,P<0.000 01);The VAS score of SP group was significantly lower than that of IP group(MD =-0.67,95%CI-0.98--0.35,P<0.0001);The ROM of SP group was significantly higher than that of IP group(MD = 2.50,95%CI 0.70-4.30,P = 0.006);There was no significant difference in reoperation rate,incision infection rate,fracture healing time,intraoperative bleeding,and hospital stay between the two groups(P>0.05).Conclusions The SP intramedullary nail approach will significantly reduce intraoperative fluoroscopy frequency and surgical time for the treatment of adult tibial fractures,which is closely related to a decrease in postoperative pain scores and improved functional prognosis of the knee joint.

Tibial fracturesFracture fixation,intramedullaryBone nails

柴巍浩、柴巍巍、金格勒、刘江伟、杨毅

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830000 乌鲁木齐,新疆医科大学研究生院

450000 郑州,河南省洛阳正骨医院膝关节外一科

830000 乌鲁木齐,新疆医科大学第一附属医院骨科中心

830000 乌鲁木齐,新疆军区总医院新疆特殊环境医学重点实验室

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胫骨骨折 骨折固定术,髓内 骨钉

国家自然科学基金天山英才-青年科技拔尖人才专项

821603562022TSYCCX0100

2024

中国骨与关节杂志
中国医疗保健国际交流促进会,北京中科康辰骨关节伤病研究所

中国骨与关节杂志

CSTPCD
影响因子:0.665
ISSN:2095-252X
年,卷(期):2024.13(1)
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