定量CT测量不同层面腰部椎后肌群体质成分的差异及相关性研究
Difference and correlation of posterior vertebral muscle composition at different levels measured by quantitative computed tomography
李新彤 1姚宁 1蔡韦 1王玲 1程晓光1
作者信息
- 1. 100035 北京,首都医科大学附属北京积水潭医院放射科
- 折叠
摘要
目的 探讨腰部椎后肌群体质成分在 L3 及 L5 椎体层面的差异及相关性.方法 对 659 名 21～60 岁的志愿者进行腰椎 CT 检查,包括 276 名男性及 383 名女性.使用定量 CT 获得 L3 及 L5 椎体层面椎后肌群的肌肉横截面积(cross-sectional muscle area,CSMA)、肌间隙脂肪面积(intra-muscular adipose area,IMAA)及肌肉脂肪浸润程度(muscle fat infiltration,MFI).使用独立样本 t 检验比较男女间椎后肌群的差异.使用配对样本 t 检验比较两个层面椎后肌群的差异.使用 person 相关及线性回归分析 L3、L5 层面椎后肌群体质成分的相关关系.结果 男性 L3 及 L5 层面椎后肌群 CSMA 大于女性(t = 27.905、7.450,P＜0.001),而 MFI 小于女性(t =-9.091、-11.755,P＜0.001).L3 层面椎后肌群 CSMA 大于 L5 层面(t = 55.850,P＜0.001),而 IMAA及 MFI 小于 L5 层面(t =-34.788、-57.774,P＜0.001).L3 及 L5 层面的 CSMA(r男性 = 0.459、r女性 = 0.365,P＜0.01)、IMAA(r男性 = 0.336、r女性 = 0.325,P＜0.01)、MFI(r男性 = 0.421、r女性 = 0.455,P＜0.01)分别呈正相关,且回归方程均有统计学意义(P＜0.001).结论 L3 及 L5 层面椎后肌群体质成分存在差异及相关性,测量层面在必要时可以进行替代.
Abstract
Objective To investigate the difference and correlation of posterior vertebral muscle composition at L3 and L5 levels.Methods CT examination of the lumbar spine was performed in 659 volunteers aged 21-60 years,including 276 males and 383 females.Cross-sectional muscle area(CSMA),intra-muscular adipose area(IMAA),and muscle fat infiltration(MFI)of the posterior vertebral muscle at L3 and L5 levels were measured by quantitative computed tomography(QCT).An independent samples t-test was used to compare the muscle composition between males and females.The paired samples t-test was used to compare the muscle composition between two levels.Correlation analysis and linear regression analysis were used to determine the relationships of muscle composition between L3 and L5 levels.Results The CSMA at L3 and L5 levels in males was higher than that in females(t = 27.905,7.450,P＜0.001),and the MFI was lower than that in females(t =-9.091,-11.755,P＜0.001).The CSMA at L3 level was higher than that at L5 level(t = 55.850,P＜0.001),while the IMAA and MFI were lower than that at L5 level(t =-34.788,-57.774,P＜0.001).The CSMA(r = 0.459,0.365,P＜0.01),IMAA(r = 0.336,0.325,P＜0.01)and MFI(r = 0.421,0.455,P＜0.01)at L3 level were positively correlated with that at L5 level,respectively.All regression equations had statistical significance(P＜0.001).Conclusions There are differences and correlations in the posterior vertebral muscle composition at L3 and L5 levels,and the measurement level can be replaced if necessary.
关键词
肌减少症/腰椎/锥束计算机体层摄影术/综合征Key words
Sarcopenia/Lumbar vertebrae/Cone-beam computed tomography/Syndrome引用本文复制引用
基金项目
国家自然科学基金青年项目(81901718)
北京积水潭医院科研优才计划(JSTYC202207)
北京积水潭医院院级科研基金(YGQ-202308)
出版年
2024
NETL
NSTL
维普
万方数据