Application of autologous platelet-rich serum in ACL reconstruction with allogenic tendon
Objective To investigate the value of anterior cruciate ligament(ACL)combined with autologous platelet rich plasma(PRP)in knee arthroscopic allogeneic tendon reconstruction in the treatment of knee ACL rupture.Methods A total of 47 patients with knee ACL rupture who met the inclusion criteria from November 2020 to November 2022 were enrolled,and the patients were divided into the experimental group(n = 24)and observation group(n = 23)according to the odd and even numbers of the last hospitalization number.Allogeneic tendon reconstruction of ACL was used in both groups.The experimental group was treated with platelet-rich plasma when reconstructing ACL,and the observation group was treated with conventional ACL reconstruction.The functional status of the knee joint was evaluated by the Lysholm score and the International Knee Documentation Committee(IKDC)score.The pain level of the knee joint was evaluated by the visual analogue scale(VAS).The postoperative follow-up was 12 months.The functional status and pain level of the knee joint in different time periods were compared between the two groups.MRI examinations were performed at 6 and 12 months after surgery.Results The scores of the two groups were better than those before surgery.The Lysholm score 64.22±10.55,IKDC score 60.22±9.77 and VAS score 6.03±1.44 of the experimental group 3 months after surgery were better than those in the observation group(72.11±9.44,68.55±10.77,4.43±1.66),and there were statistically significant differences(P<0.05).MRI score 2.12±0.87,Lysholm score 73.22±9.33,IKDC score 70.12±8.66 and VAS score 5.11±1.23 in the experimental group 6 months after surgery were better than those in the observation group(2.66±0.88,89.56±6.33,75.66±9.55,3.59±0.56),and there were statistically significant differences(P<0.05).No statistical difference was noted between the two groups 12 months after surgery(P>0.05).Knee MRI 6 months after surgery showed that the graft signal of the control group was more mixed than that of the experimental group,indicating poor healing.The graft signals in both groups were uniform and low 12 months after surgery,indicating good healing.Conclusions Autologous platelet-rich plasma can alleviate the early pain of patients in the treatment of allogeneic tendon reconstruction ACL,accelerating the process of ACL remodeling.
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