Nomogram for predicting deep vein thrombosis in the lower extremity of intertrochanteric femoral fractures
Objective To investigate the independent risk factors for lower limb deep vein thrombosis after intertrochanteric femoral fracture and to establish a nomogram prediction model accordingly.Methods Data from patients with intertrochanteric femoral fractures in the Affiliated Hospital of Xinjiang Medical University from January 2018 to December 2022 were collected,and one-way and multi-way logistic regression analyses were used to determine the independent risk factors for DVT formation in the lower limbs after intertrochanteric femoral fracture surgery,and to establish the corresponding nomogram.Receiver operating characteristic curves were plotted,the area under the curve was calculated,and the calibration and decision curves were plotted to evaluate the model performance.Results A total of 646 patients with intertrochanteric femoral fractures were included in the study,and 161 patients developed postoperative thrombosis,with an incidence of 24.77%.After univariate and multifactorial logistic regression analysis,a total of 5 variables were identified as independent risk factors for DVT formation in the lower extremity after intertrochanteric femoral fracture,including namely age>75 years(OR,1.978;95%CI,1.060-3.691),body mass index(BMI)>24(OR,2.637;95%CI,1.133-6.139),preoperative diabetes mellitus(OR,2.286;95%CI,1.143-4.569),injury mode of high-energy injury(OR,2.647;95%CI,1.414-4.953),and fracture-to-operation time>48 h(OR,6.258;95%CI,2.218-17.658).Conclusions The nomogram for lower extremity deep vein thrombosis after intertrochanteric femoral fracture constructed in this study has good predictive accuracy which will help orthopedic surgeons to intervene earlier for patients at high risk of lower extremity deep vein thrombosis after intertrochanteric femoral fracture surgery.