Age-period-cohort analysis of disease burden of osteoarthritis at different sites in China from 1990 to 2019
Objective The disease burden of osteoarthritis(OA)in different parts of China from 1990 to 2019 was systematically analyzed to provide evidence for the prevention and treatment of OA.Methods Based on the data from the Global Burden of Disease Study 2019(GBD 2019),the incidence and disability adjusted life year(DALY)of osteoarthritis at different sites in China from 1990 to 2019 were analyzed,and the age-period-cohort model was used to analyze the age,period and birth cohort effects of osteoarthritis at different sites.Results From 1990 to 2019,the number of patients with osteoarthritis in different parts of China showed an upward trend,especially in the knee.The number of patients with osteoarthritis ranked first.From 1990 to 2019,the DALY of osteoarthritis in different parts of China showed an upward trend.Standardized DALY rates in the knee,hand,hip,and other joints increased by an average of 1.1%,0.5%,0.2%and 0.2%per year,respectively.Age-period-cohort models of incidence showed that the standardized incidence of osteoarthritis of the hand peaked at the age of 55-59 years.The standardized incidence rate of osteoarthritis of the hip(OA)in the age group of 30-64 years was increasing year by year,and in the age group over 65 years was decreasing year by year.The standardized incidence of osteoarthritis of the knee peaked at the age of 50-54 years.The standardized incidence of osteoarthritis in other parts of the body increased significantly from 30 to 59 years of age.The duration and cohort RR of osteoarthritis of the hip,knee and other sites increased with time.In our country,11.83%of osteoarthritis DALY in 2019 was led by high body mass index,with a 4.62%increase in attributable DALY and a 3.68%increase in attributable DALY in 2019 compared with 1990.Conclusions According to the characteristics of osteoarthritis in different parts of China,we should take some measures to reduce the disease burden of osteoarthritis.
OsteoarthritisGlobal burden of diseaseEpidemiological modelsBody mass index
NETL
NSTL
万方数据
