首页|经髋关节外科脱位髂骨瓣植入治疗非创伤性股骨头坏死的临床疗效及影响因素分析

经髋关节外科脱位髂骨瓣植入治疗非创伤性股骨头坏死的临床疗效及影响因素分析

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目的 探讨经髋关节外科脱位入路(surgical hip dislocation,SHD)髂骨瓣打压植骨治疗非创伤性股骨头坏死(non-traumaticosteo necrosis of the femoral head,NONFH)的中短期临床疗效及影响因素.方法 回顾分析自 2014 年 1 月至 2017 年 12 月在我院骨科诊治的 56 例(62 髋)NONFH 患者,日本骨坏死研究会(Japanese Investigation Committee,JIC)分型均为 C 型,其中 C1 型 47 髋,C2 型 15 髋,均经 SHD 行股骨大转子截骨、股骨头坏死骨清除、松质骨及自体髂骨块植骨治疗.所有患者均采用 Harris 评分评估术前及术后髋关节功能,以髋关节功能优良率和 X 线影像学评估作为疗效评定指标.数据比较采用 t 检验和秩和检验,采用单因素和多因素 Logistic 回归分析影响临床结局的危险因素.结果 56 例均获得随访,随访时间(59.58±15.06)个月.末次随访时 Harris 评分为(87.50±11.84)分,较术前(55.58±8.43)明显提高,差异有统计学意义.其中优 34 髋、良 14 髋、中 1 髋、差 9 髋,保髋优良率 83.87%,9 例在 4 年内行全髋关节置换术(total hip arthroplasty,THA).X 线塌陷好转 14 髋(22.58%),无进展 5 髋(8.06%),进展 39 髋(62.90%);JIC C1 型和疼痛时间≤12个月为避免 THA的保护因素.JIC分型的 C1 和 C2 两组生存曲线差异有统计学意义(P<0.001),疼痛持续时间为≤6 个月、7~12 个月、>12 个月的 3 组生存曲线差异有统计学意义(P<0.001),72 个月时,JIC 分类 C1 型、C2 型患者的总生存率分别为 97.9%、46.5%,疼痛持续时间≤6 个月、7~12 个月、>12 个月患者的总生存率分别为 97.5%、92.9%、12.5%.结论 经 SHD 自体髂骨瓣打压植骨治疗 NONFH的中短期疗效满意,尤其是外侧柱保留完好和疼痛时间短于 1年的患者.
Clinical outcome and influencing factors of surgical hip dislocation combined with iliac bone flaps implanting in the treatment of non-traumaticosteo necrosis of the femoral head
Objective To investigate the medium-term outcomes of surgical hip dislocation(SHD)combined with impacted bone grafts and iliac bone flap implantation in the treatment of non-traumatic osteonecrosis of the femoral head(NONFH)and to define the indications for this treatment.Methods A total of 56 cases(62 hips)with non-traumatic osteonecrosis of the femoral head from January 2014 to December 2017 were included in this study.According to the JIC classification,47 hips were classified as JIC type C1,and 15 hips were classified as JIC type C2 at initial diagnosis.All patients underwent SHD surgery combined with impacted bone grafts and iliac bone flap implantation.Preoperative and postoperative clinical outcomes were assessed using the Harris hip score(HHS)to evaluate hip function before and after the operation in all patients.The excellent and good hip function ratio and X-ray imaging evaluation were used as the evaluation indexes of curative effect.Univariate and multivariate logistic regression analyses were performed to identify risk factors affecting the clinical outcome.Kaplan-Meier(K-M)analysis was applied to calculate the survival rate of the femoral head.Results At the last follow-up(59.58±15.06 months),the HHS was 87.50±11.84,which was significantly higher than that before the operation 55.58±8.43.The HHS was excellent for 34 hips,good for 14 hips,fair for 1 hip,and poor for 9 hips.The rate of excellent and good hip function was 83.87%.All nine hips with poor HHS underwent total hip arthroplasty(THA)within 4 years.The collapse situation,according to X-ray,recovered in 14 hips(22.58%),did not progress in 5 hips(8.06%),and developed in 39 hips(62.90%).JIC type C1 and pain duration≤12 months were found to protect patients from THA.There were statistical differences in the survival curves of the C1 and C2 groups of JIC classification(P<0.001),and there were statistical differences in the survival curves of the three groups with pain duration≤6 months,7-12 months,and>12 months(P<0.001).The overall survival rates of JIC type C1 and C2 were 97.9%and 46.5%,respectively.The overall survival rates of patients with pain duration≤6 months,7-12 months,and>12 months were 97.5%,92.9%,and 12.5%,respectively.Conclusions SHD combined with impacted bone grafts and iliac bone flap implantation in the treatment of NONFH had good short-term and mid-term clinical outcomes,especially for patients with retention of the lateral column of the femoral head and hip pain less than 1 year.

Femur head necrosisHip jointOrthopedic procedures

高张、凡一诺、陈志文、方汉军、黄泽青、刘予豪、周驰、陈镇秋

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510405 广东省,广州中医药大学第一临床医学院

510405 广东省,广州中医药大学第一附属医院骨科,广东省中医临床研究院

股骨头坏死 髋关节 矫形外科手术

广州市卫生健康委员会项目广州市科技计划项目

090024280012023A04J1171

2024

中国骨与关节杂志
中国医疗保健国际交流促进会,北京中科康辰骨关节伤病研究所

中国骨与关节杂志

CSTPCD
影响因子:0.665
ISSN:2095-252X
年,卷(期):2024.13(10)