Perfluoroalkyl acids(PFAAs)are a class of ubiquitous organic pollutants in aquatic environment.The PFAAs can be accumulated in various organisms,and thus induce diverse toxic effects.By studying the bioconcentration of short-chain PFAAs in Daphnia magna under exposure conditions with and without long-chain PFAAs,we herein analyzed the uptake rate constant(ku),elimination rate constant(ke),and bioconcentration factors at steady state(BCFss)of PFAAs in Daphnia magna,and subsequently attempted to uncover mechanisms underpinning the influence of long-chain PFAAs on shorter chain PFAA bioaccumulation.It revealed positive linear associations between ku or BCFss and the numbers of perfluorinated carbon,membrane-water distribution coefficients,protein-water distribution coefficients,and PFAA-protein association constants.Moreover,longer chain PFAAs inhibited the bioconcentration of shorter chain PFAAs,reducing the BCFss to 56％～80％.Such a reduction would be caused by competitive binding to proteins between longer and shorter chain PFAAs.
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