The exposure risk of fluopyram in cucumber was comprehensively evaluated for different dietary consumption groups in China based on its residual characteristics.A rapid and sensitive ultra performance liquid chromatography-tandem mass spectrometry method was developed for the determination of fluopicolide in cucumber,with limit of quantitation(LOQ)of 0.001 mg/kg and retention time of 2.6 min.The half-lives of fluopyram in cucumber was 2.6～6.7d,indicated it was an easily digestible pesticide.The final levels of fluopyram was＜LOQ～0.130mg/kg,which were lower than the maximum residue limit standard of China and the world.Probabilistic and deterministic models showed that fluopyram did not pose an unacceptable short-term dietary risk to Chinese dietary consumers(％ARfD,0.081％～2.527％),whereas there was an unacceptable long-term dietary risk(％ADI,105.740％～528.147％),of which cucumber accounted for 0.325％～1.107％.In addition,the long-term dietary risks of children aged 2～6 years(367.156％～528.147％)were significantly higher than that of other age groups(334.940％～105.740％)(p＜0.05).In summary,we should further focus on the negative effects of fluopyram exposure under multiple exposure pathways and joint risk amplification in the follow-up study,especially for vulnerable children.
维普
万方数据