中国化学快报(英文版)2008，Vol.19Issue(8) ：934-936.

A new cytotoxic 2-(2-phenylethyl)chromone from Chinese eaglewood

Jun Liu Jiao Wu You Xing Zhao Yuan Yuan Deng Wen Li Mei Hao Fu Dai
中国化学快报(英文版)2008，Vol.19Issue(8) ：934-936.
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A new cytotoxic 2-(2-phenylethyl)chromone from Chinese eaglewood

Jun Liu 1Jiao Wu 1You Xing Zhao 2Yuan Yuan Deng 1Wen Li Mei 1Hao Fu Dai1
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作者信息

  • 1. Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, China
  • 2. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, China
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Abstract

A new compound 8-chloro-5,6,7-trihydroxy-2-(3-hydroxy-4-methoxyphenethyl)-5,6,7,8-tetrahydro-4H-chromen-4-one (1) was isolated from the Chinese eaglewood [Aquilaria sinensis (Lour.) Gilg]. Its structure was elucidated on the basis of spectral data. Compound 1 showed cytotoxicity against human gastric cancer cell line (SGC-7901) in vitro by MTT method with the IC50 value of 14.6 μg/mL.

Key words

Chinese eaglewood/Aquilaria sinensis/Chromone/Cytotoxicity

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基金项目

国家重点基础研究发展计划(973计划)(2007CB116306)

Science and Technology Foundation of Chinese Academy of Agricultural Sciences(RKY0726)

Science and Technology Foundation of Chinese Academy of Agricultural Sciences(RKY0442)

出版年

2008
中国化学快报(英文版)
中国化学会

中国化学快报(英文版)

CSTPCDCSCDSCI
影响因子：0.771
ISSN：1001-8417
被引量22
参考文献量1
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