首页|Two new cucurbitane triterpenoids from Momordica charantia L.

Two new cucurbitane triterpenoids from Momordica charantia L.

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Two new cucurbitane-type triterpenoids, (23E)-5 β,19-epoxycucurbita-6,23,25-triene-3β-ol (1) and (19R, 23E)-5β,19-epoxy-19-ethoxycucurbita-6,23-diene-3 β,25-diol (2), together with three known compounds, have been isolated from the fruit of Momordica charantia L. Their structures were determined on the basis of spectral analysis. Their cytotoxic activity was tested on 5 cancer cell lines, MCF-7, HepG2, Dul45, Colon205 and HL-60 by MTT assay. Compounds 1, 3 and 4 showed weak cytotoxicity.

Momordica charantia L.Cucurbitane-typeTriterpenoidCytotoxicity

Jia Qing Cao、Yu Zhang、Jiong Mo Cui、Yu Qing Zhao

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School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China

Yanbian University Health Science Center, Yanbian University, Yanji 133000, China

supported by E&T Modern Center for Natural Products of Liaoning Province of China

2008402021

2011

10.1016/j.cclet.2010.11.033

中国化学快报(英文版)
中国化学会

中国化学快报(英文版)

CSTPCDCSCDSCI
影响因子：0.771
ISSN：1001-8417
年,卷(期)：2011.22(5)
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