首页|Pediatric ocular nanomedicines: Challenges and opportunities
Pediatric ocular nanomedicines: Challenges and opportunities
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The eye is a highly complex,yet readily accessible organ within the human body.As such,the eye is an appealing candidate target for a vast array of drug therapies.Despite advances in ocular drug therapy research,the focus on pediatric ocular drug delivery continues to be highly underrepresented due to the limited number of degenerative ocular diseases with childhood onset.In this review,we explore more deeply the reasons underlying the disparity between ocular therapies available for children and for adults by highlighting diseases that most commonly afflict children (with focus on the anterior eye) and existing prognoses,recent developments in ocular drug delivery systems and nanomedicines for children,and barriers to use for pediatric patients
PediatricOcular drug deliveryNanomedicineDrug administrationCompliance
Natasha D.Sheybani、Hu Yang
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Department of Biomedical Engineering, Virginia Commonwealth University, Richmond VA 23284, United States
Department of Chemical & Life Science Engineering, Virginia Commonwealth University,Richmond VA 23219, United States
Department of Pharmaceutics, Virginia Commonwealth University, Richmond VA 23298, United States
Massey Cancer Center, Virginia Commonwealth University, Richmond VA 23298, United States
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This work was supported by the National Institutes of Health
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