Abstract
Nucleophilic phosphine and amine catalyst-switched chemodivergent[4+1]and[3+3]annulations of allenyl imides and β,γ-enones have been developed,furnishing highly substituted 2-cyclopentenone and 2-pyranone derivatives in moderate to excellent yields.Two plausible reaction mechanisms involving two different ketene intermediates have been proposed to explain the observed chemoselectivity.Moreover,by virtue of the α,β-enone substructure of the[4+1]adducts,1,3-dipolar cycloaddition of nitrile imines has been studied in one-pot to provide various fused pyrazoline derivatives.
基金项目
国家自然科学基金(22072111)
中央高校基本科研业务费专项(2023IVA055)
NETL
NSTL
万方数据