首页|Advanced nano drug delivery systems for neuroprotection against ischemic stroke
Advanced nano drug delivery systems for neuroprotection against ischemic stroke
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Ischemic stroke(IS)represents a significant threat to brain health due to its elevated mortality and dis-ability rates.The efficacy of small-molecule neuroprotective agents has been impeded by challenges asso-ciated with traversing the blood-brain barrier(BBB)and limited bioavailability.Conversely,advanced nano drug delivery systems hold promise for overcoming these obstacles by facilitating efficient transportation across the BBB and maintaining optimal drug concentrations.This review aims to explore advanced neu-roprotective nano drug delivery systems as a means of effectively administering neuroprotective agents to the brain using pharmaceutical approaches in the treatment of IS.By examining these systems,re-searchers and clinicians can gain valuable insights and innovative concepts,illuminating the potential of advanced neuroprotective nano drug delivery systems.Leveraging these advancements can drive the progress of pioneering and efficacious therapeutic interventions for IS.
TargetBlood-brain barrierIschemic strokeNano drug deliveryNeuroprotection
Shanghai Engineering Research Center of Organ Repair,School of Medicine,Shanghai University,Shanghai 200444,China
Department of pharmacy,the International Peace Maternity and Child Health Hospital,School of Medicine,Shanghai Jiao Tong University,Shanghai 200030,China
Department of Pharmaceutical Science,School of Pharmacy,Naval Medical University,Shanghai 200433,China
School of Pharmacy,Shanghai Jiao Tong University,Shanghai 200040,China
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上海市自然科学基金Shanghai Shen Kang Center Research Physician Training Program on Innovation and Translation CapabilitiesThree-Year Action Plan for Improving Clinical Research Capacity of International Peace Maternal and Child Health Hospital,Shangh
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