Bone tissue engineering scaffold materials:Fundamentals,advances,and challenges

扫码查看

原文链接

万方数据

外文摘要：Bone damage caused by trauma and tumors is a serious problem for human health,therefore,three-dimensional(3D)scaffolding materials that stimulate and promote the regeneration of broken bone tis-sues have become the focus of current research in the field of bone damage repair.To this regard,a preferential combination of materials and preparation techniques is considered crucial for the prepara-tion of advanced bone tissue engineering scaffolds to better facilitate the regeneration of broken bone.In this review,current research advances and challenges in bone tissue engineering scaffolds are discussed and analyzed in detail.First,we elucidated the structure and self-healing mechanism of bone tissue.Sub-sequently,the main applications of different materials,including inorganic and organic materials,in bone tissue engineering scaffolds are summarized.Moreover,we overview the latest research progress of the mainstream preparation strategies of bone tissue engineering scaffolds,and provide an in-depth analysis of the different advantages of each method.Finally,promising future directions and challenges of bone tissue engineering scaffolds are systematically discussed.

外文关键词：

BiomaterialsBone defectsTissue engineeringScaffoldsOsteogenesis

作者：

Chang Xu、Zhize Liu、Xi Chen、Yang Gao、Wenjun Wang、Xijing Zhuang、Hao Zhang、Xufeng Dong

展开 >

作者单位：

Department of Cardiovascular Surgery,Central Hospital of Dalian University of Technology,Dalian 116089,China

School of Materials Science and Engineering,Dalian University of Technology,Dalian 116024,China

Department of Orthopaedics,Central Hospital of Dalian University of Technology,Dalian 116089,China

Department of Dermatology,Allergology,and Venereology,University of Lübeck,Lübeck 23562,Germany

展开 >

基金：

中央高校基本科研业务费专项中央高校基本科研业务费专项

项目编号：

DUT22QN203DUT22YG201

出版年：

2024

DOI：

10.1016/j.cclet.2023.109197

中国化学快报(英文版)

中国化学会

中国化学快报(英文版)

CSTPCD

影响因子：0.771

ISSN：1001-8417

年,卷(期)：2024.35(2)

参考文献量213