中国化学快报(英文版)2024,Vol.35Issue(2) :415-419.DOI:10.1016/j.cclet.2023.109107

Additive-free synthesis of S-substituted isothioureas via visible-light-induced four-component reaction of α-diazoesters,aryl isothiocyanates,amines and cyclic ethers

Yufen Lv Hongyu Ding Jinmao You Wei Wei Dong Yi
中国化学快报(英文版)2024,Vol.35Issue(2) :415-419.DOI:10.1016/j.cclet.2023.109107

Additive-free synthesis of S-substituted isothioureas via visible-light-induced four-component reaction of α-diazoesters,aryl isothiocyanates,amines and cyclic ethers

Yufen Lv 1Hongyu Ding 1Jinmao You 2Wei Wei 1Dong Yi3
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作者信息

  • 1. Key Laboratory of Catalytic Conversion and Clean Energy in Universities of Shandong Province,School of Chemistry and Chemical Engineering,Qufu Normal University,Qufu 273165,China
  • 2. Key Laboratory of Catalytic Conversion and Clean Energy in Universities of Shandong Province,School of Chemistry and Chemical Engineering,Qufu Normal University,Qufu 273165,China;College of Chemistry and Chemical Engineering,Shaoxing University,Shaoxing 312000,China
  • 3. School of Pharmacy,Southwest Medical University,Luzhou 646000,China
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Abstract

An additive-free and environmentally friendly strategy has been realized for the construction of S-substituted isothioureas through visible-light-induced multicomponent reaction starting from α-diazoesters,aryl isothiocyanates,amines and cyclic ethers.This methodology features simple operation,mild reaction conditions,favorable functional group tolerance,easily available starting materials and high efficiency.

Key words

Visible-light/Additive-free/Four-component reaction/S-Substituted isothioureas

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基金项目

山东省自然科学基金(ZR2021MB065)

major innovation fund of Shandong Province(2021ZDSYS23)

国家自然科学基金(21976105)

国家自然科学基金(22101237)

出版年

2024
中国化学快报(英文版)
中国化学会

中国化学快报(英文版)

CSTPCD
影响因子:0.771
ISSN:1001-8417
参考文献量57
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