中国化学快报(英文版)2024，Vol.35Issue(4) ：99-105.DOI:10.1016/j.cclet.2023.108901

Probing the dynamic thermodynamic resolution and biological activity of Cu(Ⅱ)and Pd(Ⅱ)complexes with Schiff base ligand derived from proline

Tao Yu Vadim A.Soloshonok Zhekai Xiao Hong Liu Jiang Wang
中国化学快报(英文版)2024，Vol.35Issue(4) ：99-105.DOI:10.1016/j.cclet.2023.108901
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Probing the dynamic thermodynamic resolution and biological activity of Cu(Ⅱ)and Pd(Ⅱ)complexes with Schiff base ligand derived from proline

Tao Yu 1Vadim A.Soloshonok 2Zhekai Xiao 3Hong Liu 4Jiang Wang5
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作者信息

  • 1. State Key Laboratory of Drug Research,Shanghai Institute of Materia Medica,Chinese Academy of Sciences,Shanghai 201203,China;School of Pharmacy,University of Chinese Academy of Sciences,Beijing 100049,China
  • 2. Department of Organic Chemistry I,Faculty of Chemistry,University of the Basque Country UPV/EHU,San Sebastian 20018,Spain;IKERBASQUE,Basque Foundation for Science,Bilbao 48013,Spain
  • 3. School of Pharmaceutical Science and Technology,Hangzhou Institute for Advanced Study,UCAS,Hangzhou 310024,China
  • 4. State Key Laboratory of Drug Research,Shanghai Institute of Materia Medica,Chinese Academy of Sciences,Shanghai 201203,China;School of Pharmacy,University of Chinese Academy of Sciences,Beijing 100049,China;School of Pharmaceutical Science and Technology,Hangzhou Institute for Advanced Study,UCAS,Hangzhou 310024,China
  • 5. State Key Laboratory of Drug Research,Shanghai Institute of Materia Medica,Chinese Academy of Sciences,Shanghai 201203,China;School of Pharmaceutical Science and Technology,Hangzhou Institute for Advanced Study,UCAS,Hangzhou 310024,China;Lingang Laboratory,Shanghai 200031,China
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Abstract

Schiff base metal complexes are of great importance in pharmaceutical science owing to their unique chemical properties,which enable them to exhibit diverse biological activities such as anti-bacterial,anti-oxidant,anti-inflammatory,and anti-tumor properties.Furthermore,Schiff base metal complexes can serve as reagents and catalysts in chemical reactions.This review aims to provide an overview of our re-cently published studies on Cu(Ⅱ)and Pd(Ⅱ)complexes derived from proline Schiff base ligands.We also discuss the potential applications of these metal complexes in the fields of antibacterial and chiral reso-lution.

Key words

Schiff bases/Biological activity/Tailor-made amino acids/Asymmetric synthesis/Chiral tridentate ligands/Square-planar Cu(Ⅱ)-complexes/Square-planar Pd(Ⅱ)-complexes

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基金项目

国家重点研发计划(2022YFA1302900)

国家自然科学基金(82130105)

国家自然科学基金(92253305)

国家自然科学基金(82121005)

国家自然科学基金(22177124)

Lingang Laboratory(LG-GG-202204-02)

Lingang Laboratory(LG202103-04-01)

出版年

2024
中国化学快报(英文版)
中国化学会

中国化学快报(英文版)

CSTPCD
影响因子：0.771
ISSN：1001-8417
参考文献量90
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