Abstract
Indole-derived radical cations,open-shell reactive species,display distinctive dual reactivity due to the carbon-centered radical and more electrophilic carbocation,which frequently appear in a variety of sin-gle electron oxidation reactions for synthesizing structurally diverse functionalized indoles and indo-lines.Electrocatalysis is considered as a synthetically attractive and environmentally friendly alternative for driving the single electron oxidation of indoles.Remarkable achievements in electrocatalytic indole-derived radical cation-mediated indole functionalization have been realized so far.This review compre-hensively summarizes the recent progresses in the applications of electrocatalytic indole radical cations,including C(sp2)-H functionalization,dearomative 2,3-difunctionalization,and ring-opening reaction,em-phasizing the vital single electron oxidation steps of indoles,the substrates scope and limitations,and the reaction mechanisms.
基金项目
国家自然科学基金(22261019)
江西省自然科学基金(20224BAB213004)
江西省教育厅项目(GJJ211134)
江西省教育厅项目(GJJ211137)
Ph.D.start up fund of Jiangxi Science and Technology Normal University(2021BSQD32)
NETL
NSTL
万方数据