首页|Scalable production of mesoporous titanium nanoparticles through sequential flash nanocomplexation

Scalable production of mesoporous titanium nanoparticles through sequential flash nanocomplexation

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Mesoporous titanium nanoparticles(MTNs)have emerged as an important porous semiconductor owning to their large surface area and unique electronic/optical properties.However,the fundamental research for rational manufacturing MTNs in a highly scalable manner remains a challenge.In this study,we report a two-step flash nanocomplexation(FNC)approach to large-scalable generate MTNs through the sequen-tial combination of two multi-inlet vortex mixers.By optimizing the concentrated titanium precursor,polyethylene glycol(PEG)-functionalized silane amount and pH,we have been able to produce MTNs with small particle size(31.5 nm),larger surface area(416.9 m2/g)and pore volume(0.59 cm3/g).Different from the traditional MTNs bulk,FNC-produced MTNs exhibited well-controlled manner and exceptional photo-catalytic and antibacterial properties.Importantly,the optimized MTNs outperformed commercial P25 not only in protecting ultraviolet A(UVA)-exposed skin,but also in treating P.aeruginosa-infected wound.We believe that the high controllability and scalability of sequential flash nanocomplexation method offers great opportunities in enhancing the performance of mesoporous titanium nanoparticles.

Mesoporous titanium nanoparticlesFlash nanocomplexationPhotocatalyticAntibacterialSequential

Feng Cui、Fangman Chen、Xiaochun Xie、Chenyang Guo、Kai Xiao、Ziping Wu、Yinglu Chen、Junna Lu、Feixia Ruan、Chuanxu Cheng、Chao Yang、Dan Shao

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School of Biomedical Sciences and Engineering,South China University of Technology,Guangzhou International Campus,Guangzhou 511442,China

National Engineering Research Center for Tissue Restoration and Reconstruction,South China University of Technology,Guangzhou 510006,China

Institutes for Life Sciences,School of Medicine,South China University of Technology,Guangzhou 510006,China

School of Biology and Biological Engineering,South China University of Technology,Guangzhou 510006,China

Department of Orthopedics,Academy of Orthopedics-Guangdong Province,Orthopedic Hospital of Guangdong Province,Guangdong Provincial Key Laboratory of Bone and Joint Degenerative Diseases,The Third Affiliated Hospital of Southern Medical University,Guangzhou 510665,China

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国家自然科学基金

32271388

2024

10.1016/j.cclet.2023.108681

中国化学快报(英文版)
中国化学会

中国化学快报(英文版)

CSTPCD
影响因子：0.771
ISSN：1001-8417
年,卷(期)：2024.35(4)
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