Abstract
A rhodium/diphosphine-catalyzed asymmetric cross-dehydrogenative coupling between sulfoximines and dihydrosilanes has been achieved.This is the first report on the enantioselective N-silylation of sulfox-imines.The protocol gives access to a variety of Si-stereogenic N-silylated sulfoximines in decent yield(up to 99％)with excellent stereoselectivity(up to 99％),featuring high atom economy,and a cleaner manner with H2 as the sole byproduct.The obtained bis-Si-stereogenic monohydrosilane product can be further converted into the corresponding chiral polymer with pendant sulfoximine groups.
基金项目
国家自然科学基金(22122102)
国家自然科学基金(22101120)
国家自然科学基金(22271134)
Guangdong Provincial Key Laboratory of Catalysis(2020B121201002)
Guangdong Pearl River Talent Program(2019QN01Y628)
深圳市科创委项目(RCJC20221008092723013)
Key Laboratory of Organosilicon Chemistry and Material Technology of Ministry of Education(KFJJ2022012)
NETL
NSTL
万方数据