首页|Catalytic enantioselective N-silylation of sulfoximine

Catalytic enantioselective N-silylation of sulfoximine

扫码查看
原文链接
  • NETL
  • NSTL
  • 万方数据
A rhodium/diphosphine-catalyzed asymmetric cross-dehydrogenative coupling between sulfoximines and dihydrosilanes has been achieved.This is the first report on the enantioselective N-silylation of sulfox-imines.The protocol gives access to a variety of Si-stereogenic N-silylated sulfoximines in decent yield(up to 99％)with excellent stereoselectivity(up to 99％),featuring high atom economy,and a cleaner manner with H2 as the sole byproduct.The obtained bis-Si-stereogenic monohydrosilane product can be further converted into the corresponding chiral polymer with pendant sulfoximine groups.

N-Silylation of sulfoximineChiral silylamineSi-stereogenic silanesSi-CADCAsymmetric catalysis

Xingfen Huang、Jiefeng Zhu、Chuan He

展开 >

Shenzhen Grubbs Institute and Department of Chemistry,Guangdong Provincial Key Laboratory of Catalysis,Southern University of Science and Technology,Shenzhen 518055,China

Key Laboratory of Organosilicon Chemistry and Material Technology of Ministry of Education,Hangzhou Normal University,Hangzhou 311121,China

国家自然科学基金国家自然科学基金国家自然科学基金Guangdong Provincial Key Laboratory of CatalysisGuangdong Pearl River Talent Program深圳市科创委项目Key Laboratory of Organosilicon Chemistry and Material Technology of Ministry of Education

2212210222101120222711342020B1212010022019QN01Y628RCJC20221008092723013KFJJ2022012

2024

10.1016/j.cclet.2023.108783

中国化学快报(英文版)
中国化学会

中国化学快报(英文版)

CSTPCD
影响因子：0.771
ISSN：1001-8417
年,卷(期)：2024.35(4)
  • 61