Micro/nano flow chemistry by Beyond Limits Manufacturing

Peiwen Liu ¹Fang Zhao ²Jing Zhang ²Yunpeng Bai ³Jinxing Ye ⁴Bo Bao ²Xinggui Zhou ²Li Zhang ⁵Changlu Zhou ²Xinhai Yu ⁵Peng Zuo ³Jianye Xia ³Lian Cen ²Yangyang Yang ¹Guoyue Shi ⁶Lin Xu ⁶Weiping Zhu ¹Yufang Xu ¹Xuhong Qian⁷

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作者信息

1. State Key Laboratory of Bioreactor Engineering,Shanghai Key Laboratory of Chemical Biology,School of Pharmacy,East China University of Science and Technology,Shanghai 200237,China
2. State Key Laboratory of Chemical Engineering,School of Chemical Engineering,East China University of Science and Technology,Shanghai 200237,China
3. State Key Laboratory of Bioreactor Engineering,Shanghai Collaborative Innovation Center for Biomanufacturing,East China University of Science and Technology,Shanghai 200237,China
4. School of Biomedical and Pharmaceutical Sciences,Guangdong University of Technology,Guangzhou 510006,China
5. School of Mechanical and Power Engineering,East China University of Science and Technology,Shanghai 200237,China
6. Shanghai Key Laboratory of Green Chemistry and Chemical Processes,Department of Chemistry,School of Chemistry and Molecular Engineering,East China Normal University,Shanghai 200241,China
7. State Key Laboratory of Bioreactor Engineering,Shanghai Key Laboratory of Chemical Biology,School of Pharmacy,East China University of Science and Technology,Shanghai 200237,China;Shanghai Key Laboratory of Green Chemistry and Chemical Processes,Department of Chemistry,School of Chemistry and Molecular Engineering,East China Normal University,Shanghai 200241,China
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Abstract

In September 2018,we proposed the cutting-edge concept of"Beyond Limits Manufacturing"(BLM).BLM technology is based on the three-dimensional inner engraving or precise outer engraving of ultra-fast laser,to invent micro/nano scale flow chips or devices,which makes it possible for the microform,inte-gration,economy,safety,high efficiency,green and intelligence of research,development and manufac-turing process,so as to realize transformational manufacturing in the era of Industry 4.0.In this paper,we reviewed the representative results we made in the field of micro/nano flow chemistry during the implementation of the BLM major project(December 2019 to August 2023),and discussed its application prospects in micro/nano flow chemistry.

Key words

Beyond Limits Manufacturing/Flow chemistry/Pharmaceutical manufacturing/Microreactor

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基金项目

Shanghai Municipal Development and Reform Commission()

上海市科委项目()

Shanghai STVC Group()

出版年

2024

中国化学快报(英文版)

中国化学会

中国化学快报(英文版)

CSTPCD

影响因子：0.771

ISSN：1001-8417

参考文献量98

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