Abstract
Borylation of 1,3-enynes with bis(boronate)compounds often ends up with the formation of hydrobo-rylated products,leaving the diborylation of 1,3-enynes for the formation of 1,4-diborylated allenes to be challenging.Herein,a copper-catalyzed chemo-,regio-,and stereo-selective diborylation of 1,3-enynes for the efficient construction of 1,4-diborylated allenes under base-free conditions was reported.A wide range of 1,3-enynes bearing various functional groups can participant in the reaction and afforded the corresponding 1,4-diborylated allenes in good to excellent yields,which was enabled by the protocol of Bpin to BF3K conversion.the borylcopper species was supposed to selectively attack the C-C triple bond of the 1,3-enynes.
基金项目
国家自然科学基金(22001251)
国家自然科学基金(21922112)
国家自然科学基金(22225107)
中国科学院战略规划重点项目(XDB20000000)
国家重点研发计划(2017YFA0700103)
Guizhou Provincial Science and Technology Project(2018[4007])
维普
万方数据