首页|taBOX:A water-soluble tetraanionic rectangular molecular container for conjugated molecules and taste masking for berberine and palmatine

taBOX:A water-soluble tetraanionic rectangular molecular container for conjugated molecules and taste masking for berberine and palmatine

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A water-soluble macrocycle that bears four carboxylate anions has been designed and prepared,which forms a rectangular cavity that can efficiently encapsulate discrete electron-deficient aromatic com-pounds,including berberine and palmatine.This macrocycle is revealed to be highly biocompatible and able to inhibit the bitter taste of the two drugs.

MacrocycleMultianionMolecular containerMolecular recognitionBitter taste masking

Qihan Lin、Jiabin Xing、Yue-Yang Liu、Gang Wu、Shi-Jia Liu、Hui Wang、Wei Zhou、Zhan-Ting Li、Dan-Wei Zhang

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Department of Chemistry,Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials,Fudan University,Shanghai 200438,China

国家自然科学基金国家自然科学基金国家自然科学基金国家自然科学基金

22271059219210032189073021890732

2024

中国化学快报(英文版)
中国化学会

中国化学快报(英文版)

CSTPCD
影响因子:0.771
ISSN:1001-8417
年,卷(期):2024.35(5)
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