首页|The Mn/Yb/Er triple-doped CeO2 nanozyme with enhanced oxidase-like activity for highly sensitive ratiometric detection of nitrite

The Mn/Yb/Er triple-doped CeO2 nanozyme with enhanced oxidase-like activity for highly sensitive ratiometric detection of nitrite

扫码查看
原文链接
  • NETL
  • NSTL
  • 万方数据
Long-term excessive intake of nitrite(NO2-)poses a great threat to human health,needing a simple and fast method to detect NO2-in food.Herein,via a simple and feasible strategy,Mn/Yb/Er triple-doped CeO2 nanozyme(Mn/Yb/Er/CeO2)was synthesized for highly sensitive ratiometric detection of nitrite.By doping Mn,Yb,Er into CeO2 lattice structure,Mn/Yb/Er/CeO2 nanozyme showed enhanced oxidase-like activity,obtaining a higher density of oxygen vacancy and a higher ratio of Ce3+to Ce4+than that of CeO2.The 3,3',5,5'-tetramethylbenzidine(TMB)can be effectively oxidized by Mn/Yb/Er/CeO2 to produce the oxidized TMB(oxTMB),showing a significant absorption signal at 652 nm.Additionally,nitrite can react with oxTMB to produce yellow diazotized oxTMB,which is accompanied by an elevated absorp-tion signal at 445 nm and a decreased absorption signal at 652 nm.Thus,based on the oxidase-mimetic activity of Mn/Yb/Er/CeO2 and the diazotization reaction between NO2-and oxTMB,a ratiometric col-orimetric assay was established for NO2-detection in food.Furthermore,by integrating Mn/Yb/Er/CeO2 with a smartphone,a colorimetric smartphone-sensing platform was successfully fabricated for visualiza-tion and quantitative detection of NO2-.Notably,this two-detection mode showed excellent sensitivity,selectivity,reliability and practicability in monitoring the NO2-in real samples,impling its great potential for food safety.

Mn/Yb/Er/CeO2 nanozymeOxidase-like activityNitriteRatiometric detectionTwo-detection mode

Simin Wei、Yaqing Yang、Junjie Li、Jialin Wang、Jinlu Tang、Ningning Wang、Zhaohui Li

展开 >

College of Chemistry,Institute of Analytical Chemistry for Life Science,Henan Joint International Research Laboratory of Green Construction of Functional Molecules and their Bioanalytical Applications,Zhengzhou University,Zhengzhou 450001,China

School of Basic Medical Sciences,Zhengzhou University,Zhengzhou 450001,China

National Natural Science Foundation of ChinaNational Natural Science Foundation of ChinaTackle Key Problems in Science and Technology Project of Henan Province,ChinaChina Postdoctoral Science FoundationHenan Postdoctoral FoundationProgram for Innovative Research Team(in Science and Technology)in University of Henan ProvinceExcellent Youth Foundation of Henan Scientific Committee

22004111219741252221023103862020M68232720200200922TRTSTHN002232300421021

2024

10.1016/j.cclet.2023.109114

中国化学快报(英文版)
中国化学会

中国化学快报(英文版)

CSTPCD
影响因子：0.771
ISSN：1001-8417
年,卷(期)：2024.35(6)
  • 2