首页|Exploring the functional roles of small-molecule metabolites in disease research:Recent advancements in metabolomics

Exploring the functional roles of small-molecule metabolites in disease research:Recent advancements in metabolomics

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Metabolism encompasses a series of intricate biochemical processes that are vital for the sustenance of life in organisms.Metabolomics,an essential scientific discipline,is a field of study within the broader domain of systems biology that focuses on the comprehensive analysis of small molecules,known as metabolites including lipids,coenzymes,etc.,which are synthesized during metabolism.With the contin-uous development of metabolomics,the multiple biological functions of metabolites are constantly being discovered,encompassing signal transduction and enzyme stimulation,while concurrently exhibiting as-sociations with afflictions like cancer and diabetes.The comprehension of metabolite functionalities and their intricate interplay with disease conditions assumes paramount importance in both disease-focused research endeavors and the development of diagnostic tools.This scholarly exposition undertakes an ex-tensive review of recent advancements in the investigation of functional roles assumed by metabolites,with specific emphasis on metabolites in lipid synthesis,glucose metabolism and exogenous metabolites.

MetabolitesSmall moleculesBiological functionsPhysiological processesDiseases

Aolei Tan、Xiaoxiao Ma

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Department of Precision Instrument,Tsinghua University,Beijing 100084,China

2024

中国化学快报(英文版)
中国化学会

中国化学快报(英文版)

CSTPCD
影响因子:0.771
ISSN:1001-8417
年,卷(期):2024.35(8)