首页|Transition-metal-catalyzed remote meta-C-H alkylation and alkynylation of aryl sulfonic acids enabled by an indolyl template
Transition-metal-catalyzed remote meta-C-H alkylation and alkynylation of aryl sulfonic acids enabled by an indolyl template
扫码查看
点击上方二维码区域，可以放大扫码查看
原文链接
万方数据
维普
Transition-metal-catalyzed remote sp2C-H functionalization of aryl sulfonic acids was hardly ever real-ized owing to competitive ortho-C-H functionalization of aryl sulfonates and electron-deficient nature of phenyl ring.Herein,with the assistance of a practical biaryl indolyl directing template,palladium-catalyzed remote sp2C-H alkylation of aryl sulfonic acids have been achieved in moderate to good yields with exclusive meta selectivity.Moreover,remote meta-selective C-H alkynylation of aryl sulfonic acids was also accomplished with a rhodium catalyst.These meta-C-H functionalized products proved to be the superior synthetic precursors,which are difficult to access using the conventional strategy.
Pengfei Zhang、Qingxue Ma、Zhiwei Jiang、Xiaohua Xu、Zhong Jin
展开 >
College of Chemistry,State Key Laboratory of Elemento-Organic Chemistry,Nankai University,Tianjin 300071,China
College of Chemistry,State Key Laboratory of Elemento-organic Chemistry,Nankai University,Tianjin 300071,China
Key Laboratory of Xinjiang Native Medicinal and Edible Plant Resource Chemistry,College of Chemistry and Environmental Sciences,Kashi University,Kashgar 844007,China
万方数据
维普
