Abstract
Nanozymes are the paradigm for bridging inorganic nanomaterials with biology and environment for tak-ing the spontaneous responsibilities to outplay natural enzymes.Metal-organic frameworks(MOFs)are mesoporous materials of inorganic-organic coordination,bearing ampoules of active/target sites and hav-ing the tendency to mimic natural enzymes.Thus MOF-based nanozymes(NZs)could be recognized for their tremendous potential for bio-catalysis.However,MOFs are of four types namely:modified MOFs,pristine MOFs,MOF-derived materials and MOFs comprised of natural enzymes.The MOFs-based NZ modulated via ultrasound,light,and heat revealed diversified applications.This article is concentrated on different methods for the preparation of MOF-based NZ for mimicking the responses of catalases,multi-functional enzymes,oxidases,superoxide dismutase,hydrolases,and peroxidases,progress and challenges of MOFs/MOF-based materials for exploiting their recent and futuristic approaches in biomedical sector.