首页|Metal organic framework modulated nanozymes tailored with their biomedical approaches

Metal organic framework modulated nanozymes tailored with their biomedical approaches

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Nanozymes are the paradigm for bridging inorganic nanomaterials with biology and environment for tak-ing the spontaneous responsibilities to outplay natural enzymes.Metal-organic frameworks(MOFs)are mesoporous materials of inorganic-organic coordination,bearing ampoules of active/target sites and hav-ing the tendency to mimic natural enzymes.Thus MOF-based nanozymes(NZs)could be recognized for their tremendous potential for bio-catalysis.However,MOFs are of four types namely:modified MOFs,pristine MOFs,MOF-derived materials and MOFs comprised of natural enzymes.The MOFs-based NZ modulated via ultrasound,light,and heat revealed diversified applications.This article is concentrated on different methods for the preparation of MOF-based NZ for mimicking the responses of catalases,multi-functional enzymes,oxidases,superoxide dismutase,hydrolases,and peroxidases,progress and challenges of MOFs/MOF-based materials for exploiting their recent and futuristic approaches in biomedical sector.

MOFNanozymeCatalysisBiomedicineTheranostics

Manoj Kumar Sarangi、L.D Patel、Goutam Rath、Sitansu Sekhar Nanda、Dong Kee Yi

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Department of Pharmaceutics,Amity Institute of Pharmacy,Amity University,Lucknow 201313,India

Department of Pharmaceutics,Parul Institute of Pharmacy,Parul University,Vadodara 391760,India

Department of Pharmaceutics,School of Pharmaceutical Sciences,Siksha'O'Anusandhan University,Bhubaneswar 751030,India

Department of Chemistry,Myongji University,Yongin 03674,Republic of Korea

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2024

10.1016/j.cclet.2023.109381

中国化学快报(英文版)
中国化学会

中国化学快报(英文版)

CSTPCD
影响因子：0.771
ISSN：1001-8417
年,卷(期)：2024.35(11)