Retrospective studies of volume-OXygeneration index in predicting the effect of early non-invasive positive pressure ventilation in patients with type Ⅰ Respiratory failure
Objective To observe the predictive value of Volume OXygeneration(VOX)index for early non-invasive positive pressure ventilation(NIPPV)treatment in patients with type Ⅰ Respiratory failure.Methods Retrospective analysis was made on the patients with type Ⅰ Respiratory failure admitted to the intensive care medicine from September 2019 to September 2022,who received early NIPPV treatment.After screening according to the discharge standard,they were grouped according to the NIPPV 2-hour VOX index.The observation group was VOX Youden index＞20.95(n=69),and the control group was VOX index ≤20.95(n=64).Collect patient baseline data and NIPPV 2-hour,12-hour,and 24-hour arterial blood gas values,and calculate NIPPV outcomes,intubation status,NIPPV usage time,hospital stay,and mortality rate.Results There was a statistically significant difference in respiratory rate(RR)between the baseline data onto the two groups of patients,but others not.After early NIPPV treatment,the 2-hour oxygenation index(P/F)[(182.5±66.14)vs.(144.1±63.6)mm Hg,P＜0.05]of the observation group showed a more significant increase.The failure rate of NIPPV intubation within 12 hours was lower(4.35％vs.32.81％,P＜0.05),the success rate of NIPPV withdrawal from 24 hours was higher(40.58％vs.0％,P＜0.05),and the failure rate of NIPPV intubation was lower(4.35％vs.46.88％,P＜0.05).The comparison of treatment outcomes showed that the intubation rates in the observation group(4.35％vs.67.19％,P＜0.05)was lower.The threshold of NIPPV 2-hour VOX index 20.95 was used as a predictor of Tracheal intubation,with sensitivity of 74.7％and specificity of 93.5％.Conclusion In the early NIPPV treatment of patients with type Ⅰ Respiratory failure,the NIPPV 2-hour VOX index＞20.91 is taken as the evaluation index,which can better to predict the improvement in hypoxia and the risk of NIPPV failure Tracheal intubation,and has clinical significance.
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