肺移植受者发生吞咽障碍危险因素的Meta分析和系统评价
Meta-analysis and systematic review of risk factors for dysphagia in lung transplant recipients
朱岩 1兰美娟 1梁江淑渊 1蔡凌云 1郭璐瑶 1顾培培 1曾妃1
作者信息
- 1. 浙江大学医学院附属第二医院护理部(浙江 杭州 310000)
- 折叠
摘要
目的 通过Meta分析了解肺移植受者发生吞咽障碍的危险因素.方法 计算机检索中国知网、维普数据库、万方数据库、中国生物医学文献数据库、PubMed、Cochrane Library、Embase、CINAHL、Web of Science、Scopus、ProQuest数据库中关于肺移植术后吞咽障碍危险因素的队列研究和病例对照研究,检索时限为建库至2023年7月,经文献筛选、数据提取、质量评价后,采用Rev Man 5.4和Stata17.0软件进行Meta分析.结果 最终纳入12篇文献,Meta分析结果示:肺移植受者吞咽障碍的发生率为67％(95％CI 0.59～0.75,I2=92.44％,P＜0.001),肺移植受者发生吞咽障碍的危险因素有3个,存在重新插管(OR=5.34,95％CI 3.07～9.28,I2=0％,P＜0.001)、使用机械通气(OR=4.25,95％CI2.95～6.12,I2=0％,P＜0.001)、使用体外生命支持(OR=2.13,95％CI 1.69～2.67,I2=0％,P＜0.001).结论 重新插管、机械通气和体外生命支持的肺移植受者,术后更易发生吞咽障碍,护理人员可结合危险因素,针对性地制订护理措施,降低肺移植患者术后吞咽障碍的发生率.
Abstract
Objective To investigate the risk factors of dysphagia in lung transplant recipients through meta-analysis.Method Cohort studies and case-control studies on risk factors for dysphagia after lung transplantation in Science,Scopus and ProQuest databases were searched from the establishment of the database to July 2023.After literature screening,data extraction and quality evaluation,Meta-analysis was performed using Rev Man 5.4 and Stata17.0 software.Results 12 literatures were included,and the results of meta-analysis showed:The incidence of dysphagia in lung transplant recipients was 67％(95％CI 0.59～0.75,I2=92.44％,P＜0.001).There were three risk factors for dysphagia in lung transplant recipients,namely,reintubation(OR=5.34,95％CI 3.07～9.28,I2=0％,P＜0.001),mechanical ventilation(OR=4.25,95％CI 2.95～6.12,I2=0％,P＜0.001),extracorporeal life support(OR=2.13,95％CI 1.69～2.67,I2=0％,P＜0.001).Conclusions Lung transplant recipients with re-intubation,mechanical ventilation and extracorporeal life support are more likely to have dysphagia after surgery.Nursing staff can combine risk factors and formulate targeted nursing measures to reduce the incidence of dysphagia after lung transplantation.
关键词
肺移植/吞咽障碍/危险因素/Meta分析Key words
Lung transplantation/dysphagia/risk factors/meta-analysis引用本文复制引用
基金项目
浙江省医药卫生科技计划项目(2021KY713)
浙江省医药卫生科技计划项目(2023KY770)
出版年
2024
NETL
NSTL
万方数据