Objective To analyze the factors that influence the height development of children and adolescents aged 3 to 16 years in Chengguan District of Lhasa of Xizang Autonomous Region,China.Methods During the period from August 2021 to June 2022,a convenient sampling method was used to select 100 children and adolescents aged 3-16 years residing in Chengguan District of Lhasa of Xizang Autonomous Region,China.The subjects'physical measurement indicators,Tanner stage,height development questionnaire,wrist bone age,sex hormones,and nutritional biochemical indicators were carefully collected.The factors that influence height development were analyzed using univariate and multivariate logistic regression analyses.Furthermore,the receiver operating characteristic(ROC)curves were constructed to visualize the effects of these influential factors.Results The study involved a total of 100 children and adolescents,with 51(51.0％)participants in the tall stature group and 49(49.0％)participants in the low stature group.Significant differences were observed between the two groups in terms of height difference relative to the national average,body weight,waist circumference,luteinizing hormone level,the percentage of individuals with an abnormal luteinizing hormone level,follicle stimulating hormone level,and bone age[x2(t)=13.6,2.65,2.47,-2.58,10.9,-2.95,11.8,all P＜0.05].A univariate logistic regression analysis revealed that body mass,waist circumference,the percentage of individuals with an abnormal luteinizing hormone level,follicle stimulating hormone level,and bone age are factors that possibly affect height development(OR=1.05,1.05,4.56,1.18,2.99,all P＜0.05).Furthermore,a multivariate logistic regression analysis revealed waist circumference,the percentage of individuals with an abnormal luteinizing hormone level,and bone age as independent factors influencing height development(OR=1.10,7.01,3.14,all P＜0.05).The receiver operating characteristic(ROC)curve analysis showed that the values of the area under the curve were 0.65,0.65,0.67,and 0.75 respectively for waist circumference,the percentage of individuals with an abnormal luteinizing hormone level,bone age,and their combination(all P＜0.05).Conclusion Waist circumference,the percentage of individuals with an abnormal luteinizing hormone level,and bone age appear to be critical factors influencing the height development of children and adolescents In Chengguan District of Lhasa of Xizang Autonomous Region,China.
ChildAdolescentBody heightRoot cause analysisAge determination by skeletonForecasting
NETL
NSTL
万方数据
