首页|经鼻高流量湿化氧疗在阻塞性睡眠呼吸暂停低通气综合征中的应用

经鼻高流量湿化氧疗在阻塞性睡眠呼吸暂停低通气综合征中的应用

Application of high-flow nasal cannula oxygen therapy in obstructive sleep apnea hypopnea syndrome

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随着时代的发展,医疗技术水平不断进步,氧气疗法已经成为临床诊治中不可或缺的一部分,是临床中为患者提供的基础性诊治方式,而经鼻高流量湿化氧疗(HFNC)能够在对患者进行呼气末正压效应、加温加湿、持续对鼻咽部生理无效腔冲刷的同时,还具有舒适性,因此取代普通氧疗及部分无创通气诊治,成为临床治疗的首选.HFNC由于其独特的生理效应,广泛运用于临床当中.而阻塞性睡眠呼吸暂停低通气综合征(OSAHS)为常见睡眠障碍性疾病,导致患者睡眠结构紊乱,反复发生憋醒等症状,增加心血管等疾病的发病及病死率,因此及时进行科学有效的治疗方式十分重要.HFNC不仅能够提供高流量气流及相应气道压力,还具有较高耐受性,因此已逐渐运用于OSAHS患者的治疗中,该研究针对HFNC的生理效应及在OSAHS中的应用进行研究,希望为同行业学者提供理论依据.
With the development of the times and the continuous advancement of medical technology,oxygen therapy has become an indispensable part of clinical diagnosis and treatment,serving as the fundamental form of care provided to patients.High-flow nasal cannula oxygen therapy is able to exert an end-expiratory pressure effect,provide heating and humidification,and continuously flush the physiologically ineffective cavity of the nasopharyngeal area.Additionally,due to its comfort,high-flow nasal cannula oxygen therapy has replaced ordinary oxygen therapy and some forms of noninvasive ventilation in clinical settings,becoming the preferred choice for clinical treatment.High-flow nasal cannula oxygen therapy is widely utilized in clinical practice due to its unique physiological effects.Obstructive sleep apnea hypopnea syndrome is a common sleep disorder that leads to disrupted sleep patterns,recurrent occurrence of suffocation and wakefulness,and increased morbidity and mortality of cardiovascular diseases.Therefore,it is crucial to initiate scientific and effective treatments promptly.High-flow nasal cannula oxygen therapy not only provides a high-flow airflow and corresponding airway pressure,but also has a high level of tolerability,making it gradually adopted in the treatment of patients with obstructive sleep apnea hypopnea syndrome.In this review,we investigate the physiological effects of high-flow nasal cannula oxygen therapy and its application in obstructive sleep apnea hypopnea syndrome,with the objective of providing a theoretical basis for scholars working in the same field.

Sleep apnea,obstructiveOxygen inhalation therapyHumidityPositive-pressure respirationReview

刘宝德、郑相、宓奔

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杭州市第一人民医院急诊科,杭州 310006

睡眠呼吸暂停,阻塞性 氧吸入疗法 湿度 正压呼吸 综述

浙江省杭州市生物医药和健康产业发展扶持专项项目

2023WJC202

2024

中国基层医药
中华医学会,安徽医科大学

中国基层医药

影响因子:1.003
ISSN:1008-6706
年,卷(期):2024.31(7)
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