Objective To investigate the effect of programmed blood glucose management model on blood glucose control and prognosis in patients with sepsis and diabetes mellitus.Methods Seventy-six patients with sepsis and diabetes mellitus who received treatment at the Fifth Hospital Affiliated to Wenzhou Medical University(Lishui Central Hospital)were included in this study.According to the implementation time of programmed blood glucose management model,the patients were divided into a routine group(n=37;receiving routine nursing between January 2021 and December 2022)and an experimental group(n=39,receiving routine nursing and programmed blood glucose management).Length of hospital stay,28-day mortality rate,blood glucose control level(glycosylated hemoglobin level,blood glucose variability,incidence of hypoglycemia,fasting blood glucose level,and 2-hour postprandial glucose level),and health status(Medical Outcomes Study-36-Item Shot-Form Health Status Survey)as well as incidence of adverse events were compared between the two groups.Results The length of hospital stay in the experimental group was(14.85±2.77)days,which was significantly shorter than that in the routine group[(17.42±3.24)days,t=3.72,P＜0.001].The 28-day mortality rate in the experimental group was 7.69％(3/39),which was significantly lower than that in the control group[24.32％(9/37),x2=3.95,P=0.047].The level of glycated hemoglobin and blood glucose variability in the experimental group were 10.4(8.5,12.1)mmol/L and(31.54±7.16)％,which were significantly lower than those in the routine group[12.8(8.9,15.3)mmol/L,(45.63±12.19)％,Z=6.88,P＜0.001;t=6.18,P＜0.001].There was no significant difference in the incidence of hypoglycemia between the experimental and routine groups[10.81％(4/37)vs.5.13％(2/39),x2=0.84,P=0.358].After the intervention,the experimental group had higher scores in various dimensions of the 36-Item Shot-Form Health Status Survey,including limitations[(72.21±5.37)points],bodily pain[(82.98±6.41)points],general health[(81.32±6.23)points],and physical function[(71.43±5.22)points]compared with the routine group[(68.39±6.21)points,(78.35±6.17)points,(74.50±7.57)points,(65.57±6.96)points,t=2.87,P=0.005;t=3.20,P=0.002;t=4.29,P＜0.001;t=4.16,P＜0.001].There was no significant difference in the incidence of adverse events between the experimental and routine groups[10.26％(4/39)vs.13.51％(5/37),x2=0.19,P=0.660].Conclusion Programmed blood glucose management model can improve blood glucose control level and prognosis of patients with sepsis and diabetes mellitus.
维普
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