Objective To explore the predictive value of respiratory rate-oxygenation(ROX)index for the failure of high-flow nasal cannula oxygen therapy(HFNC)in patients with severe pneumonia and respiratory failure.Methods A retrospective analysis was conducted on the medical records of 124 patients with severe pneumonia combined with respiratory failure admitted to Xuzhou Central Hospital from June 2021 to February 2023.The clinical data of the subjects were collected,and patients were divided into a treatment success and a treatment failure group based on the treatment results of HFNC.The influencing factors for HFNC treatment failure were screened,and the predictive value of ROX index on the treatment effect of HFNC in patients with severe pneumonia combined with respiratory failure was analyzed.Results Among 124 patients with severe pneumonia and respiratory failure,81 cases(65.32％)achieved treatment success,while 43 cases(34.68％)experienced treatment failure.The failure group had higher APACHE Ⅱscore and lower serum albumin and ROX index compared to the success group(P＜0.05).Logistic regression analysis showed that higher APACHE Ⅱ scores,lower serum albumin,and lower ROX index were the influencing factors for the failure of HFNC treatment(P＜0.05).The receiver operating characteristic curve(ROC)analysis showed that the sensitivity of the ROX index in predicting HFNC failure in patients with severe pneumonia and respiratory failure was 88.37％,the specificity was 71.60％,and the area under the curve(AUC)was 0.794(95％CI:0.717-0.872).Conclusion The ROX index can be used to predict the outcome of HFNC in patients with severe pneumonia and respiratory failure,and its predictive efficacy is good.
Severe pneumoniaRespiratory failureHigh-flow nasal cannula oxygen therapyRespiratory rate-oxygenation indexPredictive performance
维普
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