Objective To investigate the effect of clinical factors on the short-term prognosis of patients with acute carbon monoxide toxic heart disease.Methods The clinical data of 100 patients with acute carbon monoxide poisoning admitted to our hospital from August 2020 to February 2023 were retrospectively analyzed.Among them,60 patients with toxic heart disease were divided into group A,group B and group C according to the severity of heart disease.There were 31 cases of mild heart disease in group A,20 cases of moderate heart disease in group B,9 cases of severe heart disease in group C,and 40 cases without toxic heart disease as control group.Patient demographics were recorded,and levels of creatine kinase myocardial band(CK-MB)and cardiac troponin I(cTnI)were compared at admission,3 days after admission,and at discharge.Binary regression analysis and Spearman correlation analysis were employed to assess the relationship between clinical factors and short-term prognosis.Results APACHE Ⅱ score,hospitalization time and coma time in group C were significantly higher than those in groups A and B(P<0.05).At 3 days after admission,the levels of CK-MB and cTnI in group C were significantly higher than those in group A and group B(P<0.05).Multivariate analysis showed that cTnI was the main factor affecting the short-term prognosis of patients with acute carbon monoxide toxic heart disease(P<0.05),but CK-MB was not associated with short-term prognosis(P>0.05).Conclusion The level of cTnI is significantly correlated with the severity of acute carbon monoxide poisoning heart disease,and the increase of cTnI level indicates the aggravation of the patient's condition.
维普
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